Affinity DataKi: 2.00E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 4.70E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 4.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 8.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 1.16E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 1.19E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 1.45E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 1.48E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 1.57E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 2.88E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 3.15E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataKi: 4.66E+4nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
TargetDNA polymerase iota(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant DNA polymerase iota expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at ...More data for this Ligand-Target Pair
TargetDNA polymerase eta(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant DNA polymerase eta expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at 2...More data for this Ligand-Target Pair
TargetDNA polymerase eta(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant DNA polymerase eta expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at 2...More data for this Ligand-Target Pair
TargetDNA polymerase iota(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant DNA polymerase iota expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at ...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate preincubated for 30 mins followed by substrate addition by fluorescence-based HTS ass...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate preincubated for 30 mins followed by substrate addition by fluorescence-based HTS ass...More data for this Ligand-Target Pair
TargetProliferating cell nuclear antigen(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to full length human PCNA expressed in Escherichia coli BL21(DE3) assessed as inhibition of interaction with N-terminal 5-carboxyflu...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
TargetDNA polymerase kappa(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
TargetDNA polymerase kappa(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
TargetDNA polymerase kappa(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
TargetDNA polymerase kappa(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of FAM-labelled polkappa-RIR peptide from recombinant human C-terminal Rev1 (1158 to 1251 residues) expressed in Escherichia coli BL21(D...More data for this Ligand-Target Pair
TargetDNA polymerase iota(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human DNA polymerase iota preincubated for 15 mins followed by replicating non-damaged DNA substrate addition measured after 30 mins in...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 48(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
TargetDNA polymerase kappa(Homo sapiens (Human))
University Of Connecticut Health Center
Curated by ChEMBL
University Of Connecticut Health Center
Curated by ChEMBL
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea...More data for this Ligand-Target Pair