Affinity DataKi: 160nMAssay Description:Inhibitory activity of the compound against human S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Inhibitory activity of the compound against P. falciparum S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Inhibitory activity of the compound against human S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
Affinity DataKi: 7.90E+3nMAssay Description:Inhibitory activity of the compound against human S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
Affinity DataKi: 8.80E+3nMAssay Description:Inhibition of human SAHHMore data for this Ligand-Target Pair
Affinity DataKi: 1.24E+4nMAssay Description:Inhibition of human SAHHMore data for this Ligand-Target Pair
Affinity DataKi: 2.03E+4nMAssay Description:Inhibition of human SAHHMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PIM3 (1 to 326 end residues) expressed in baculovirus infected sf21 cells using S6K...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 0.490nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged PIM1 (1 to 313 end residues) expressed in baculovirus infected sf21 cells using S6K...More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PIM3 (unknown origin) using FL-Peptide 1 (5-FAM-AKRRRLSSLRA-COOH) substrate incubated for 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Functional inhibition of ET-1 induced [Ca2+] increase in human Girardi heart (hGH) cells, which express Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Inhibitory activity against 125 I-labeled ET-1 binding to Endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 0.840nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 0.880nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PIM3 (1 to 326 end residues) expressed in baculovirus infected sf21 cells using S6K...More data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity towards endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity towards Endothelin B receptor in human girardi heart cell membranesMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PIM3 (unknown origin) using FL-Peptide 1 (5-FAM-AKRRRLSSLRA-COOH) substrate incubated for 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against 125 I-labeled ET-1 binding to Endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PIM3 (unknown origin) using FL-Peptide 1 (5-FAM-AKRRRLSSLRA-COOH) substrate incubated for 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged PIM1 (1 to 313 end residues) expressed in baculovirus infected sf21 cells using S6K...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibitory activity against 125 I-labeled ET-1 binding to Endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PIM3 (unknown origin) using FL-Peptide 1 (5-FAM-AKRRRLSSLRA-COOH) substrate incubated for 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Binding affinity towards endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PIM1 (unknown origin) by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Binding affinity towards endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of PIM1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity towards endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair