Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory effect of compound on the release of Beta-glucuronidase in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory effect of compound on the release of Beta-glucuronidase in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibitory effect of compound on the release of Beta-glucuronidase in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of radioligand binding to human histamine H1 receptorMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of radioligand binding to human adrenergic alpha1a receptorMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human histamine H4 receptor at 10 uM by radioligand displacement assayMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human histamine H2 receptor at 10 uM by radioligand displacement assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat mGlu4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of radioligand binding to human adrenergic alpha1d receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of radioligand binding to human histamine H1 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat mGlu1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of radioligand binding to human dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibitory effect of compound on the release of Beta-glucuronidase in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory effect of compound on the release of Beta-glucuronidase in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory effect of compound on the release of Beta-glucuronidase in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory effect of compound on the release of Beta-glucuronidase in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory effect of compound on the release of Beta-glucuronidase in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory effect of compound on the release of lysozyme in rat neutrophils stimulated with fMLP/CBMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 4.31E+4nMAssay Description:Inhibition of mushroom tyrosinase activity after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 4.34E+4nMAssay Description:Inhibition of mushroom tyrosinase activity after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 4.61E+4nMAssay Description:Inhibition of mushroom tyrosinase activity after 150 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 7.11E+4nMAssay Description:Inhibition of mushroom tyrosinase activity after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 7.89E+4nMAssay Description:Inhibition of mushroom tyrosinase activity after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 8.44E+4nMAssay Description:Inhibition of mushroom tyrosinase activity after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 150 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.44E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.68E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.72E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 150 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.76E+5nMAssay Description:Inhibition of mushroom tyrosinase after 30 minsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 150 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 150 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.97E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 150 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 2.03E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 90 mins by spectrophotometryMore data for this Ligand-Target Pair