Affinity DataKi: 4.30E+3nM ΔG°: -31.9kJ/mole IC50: 1.02E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of catalytic activity of LRS (unknown origin) by aminoleucylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24.7nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 29.3nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 40.4nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 58.6nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of catalytic activity of LRS (unknown origin) by aminoleucylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 198nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 252nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 337nMAssay Description:Inhibition of catalytic activity of LRS (unknown origin) by aminoleucylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 412nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 422nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 694nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 787nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:Kinases used were human-derived JAK1, JAK2, JAK3, and TYK2 (Millipore, Germany). Each of these kinases was diluted with a suitable buffer solution as...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.34E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.88E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 4.34E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 5.71E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 6.76E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+5nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+5nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+5nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair