Affinity DataIC50: 20nMAssay Description:Inhibition of 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Farnesyltransferase catalyzed transfer of the FPP moiety to dansyl-GCVLSMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of Farnesyltransferase catalyzed transfer of the FPP moiety to dansyl-GCVLSMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Universit£
Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of Farnesyltransferase catalyzed transfer of the FPP moiety to dansyl-GCVLSMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 production by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of 5-hydroxyeicosatetraenoic acid production by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair