Affinity DataKi: 0.0450nMAssay Description:Inhibition of p53 protein binding to MDM2 in human SJSA1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of wild type p53 protein binding to MDM2 in human HCT116 cells by immunoblot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.880nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Antagonist at CCR5 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to BRD4-BD2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate assessed as inhibition constant incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Antagonist potency against histamine H3 receptor in an electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Antagonist potency against histamine H3 receptor in an electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
West China Hospital
Curated by ChEMBL
West China Hospital
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity to EZH2 mutant (unknown origin) assessed as apparent inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
West China Hospital
Curated by ChEMBL
West China Hospital
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity to wild-type EZH2 (unknown origin) assessed as apparent inhibition constantMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as a substrate assessed as inhibition constant incubated for 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Antagonist potency against histamine H3 receptor in an electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of wild type p53 protein binding to MDM2 in human HCT116 cells by immunoblot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant preincubated with compound for 15 mins by microplate read...More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity to BRD4-BD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 355nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
West China Hospital
Curated by ChEMBL
West China Hospital
Curated by ChEMBL
Affinity DataKi: 710nMAssay Description:Binding affinity to N-terminal 6His-tagged recombinant human DHODH expressed in Escherichia coli strain BL21 (DE3) by isothermal titration calorimetr...More data for this Ligand-Target Pair
Affinity DataKi: 8.50E+3nMAssay Description:Inhibition of wild type p53 protein binding to MDM2 in human HCT116 cells by immunoblot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0130nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as diphenolase activity incubated for 20 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of human VEGFR-2 using poly(Glu, Tyr) as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0433nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as diphenolase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activity preincubated for 20 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as a substrate by UV-2450 spectrophotometeric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human mTORMore data for this Ligand-Target Pair
Affinity DataIC50: <0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
Affinity DataIC50: <0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
Affinity DataIC50: <0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
Affinity DataIC50: <0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair