Report error Found 30 with Last Name = 'tomlinson' and Initial = 'm'
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 GripTite cells pre-incubated for 5 mins followed by [3H]5-HT addition by [3H]5-HT uptake assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 GripTite cells pre-incubated for 5 mins followed by [3H]5-HT addition by [3H]5-HT uptake assayMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 GripTite cells pre-incubated for 5 mins followed by [3H]5-HT addition by [3H]5-HT uptake assayMore data for this Ligand-Target Pair
Affinity DataKi: 77nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 227nMAssay Description:Inhibition of wild type human SERT expressed in HEK293 GripTite cells pre-incubated for 5 mins followed by [3H]5-HT addition by [3H]5-HT uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Tested for MCH-1 induced [Ca2+] release from CHO cells transfected with human MCH-1RMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Tested for MCH-1 induced [Ca2+] release from CHO cells transfected with human MCH-1RMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Tested for MCH-1 induced [Ca2+] release from CHO cells transfected with human MCH-1RMore data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:Tested for MCH-1 induced [Ca2+] release from CHO cells transfected with human MCH-1RMore data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:Inhibitory activity against human 5-HT2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 349nMAssay Description:Inhibitory activity against human 5-HT2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against human 5-HT2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 442nMAssay Description:Inhibitory activity against human 5-HT2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibition of human recombinant phospho-MK2 (36-400) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Displacement of [8-3H]ATP from human recombinant phospho-MK2 (36-400) by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibitory activity against human 5-HT2C receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of [8-3H]ATP from human recombinant MK2 (36-400) by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibitory activity against human 5-HT2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant phospho-MK2 (36-400) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Displacement of [8-3H]ATP from human recombinant MK2 (41-364) by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Displacement of [8-3H]ATP from human recombinant MK2 (36-400) by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [8-3H]ATP from human recombinant MK2 (41-364) by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate in presence of NADPMore data for this Ligand-Target Pair