Report error Found 177 with Last Name = 'tahir' and Initial = 'mn'
Affinity DataIC50: 32nMpH: 8.0 T: 25°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 89nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 10 mins followed by substrate addition measured after 20 m...More data for this Ligand-Target Pair
Affinity DataIC50: 102nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of horse serum BChE using butyrylthiocholine iodide as substrate pretreated for 10 mins followed by substrate addition measured after 20 m...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human ecto-5' nucleotidase expressed in COS7 cell membranes assessed as inorganic phosphate release using AMP as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 177nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human ecto-5' nucleotidase expressed in COS7 cell membranes assessed as inorganic phosphate release using AMP as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 181nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant rat ecto-5' nucleotidase expressed in COS7 cell membranes assessed as inorganic phosphate release using AMP as substrate uM...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human ecto-5' nucleotidase expressed in COS7 cell membranes assessed as inorganic phosphate release using AMP as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 283nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 314nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human ecto-5' nucleotidase expressed in COS7 cell membranes using AMP as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 321nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 387nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant human ecto-5' nucleotidase expressed in COS7 cell membranes assessed as inorganic phosphate release using AMP as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 466nMpH: 8.0 T: 25°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant rat ecto-5' nucleotidase expressed in COS7 cell membranes assessed as inorganic phosphate release using AMP as substrate uM...More data for this Ligand-Target Pair
Affinity DataIC50: 564nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 583nMpH: 8.0 T: 25°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Affinity DataIC50: 592nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of recombinant rat ecto-5' nucleotidase expressed in COS7 cell membranes assessed as inorganic phosphate release using AMP as substrate uM...More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant human ecto-5' nucleotidase expressed in COS7 cell membranes assessed as inorganic phosphate release using AMP as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 694nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 899nMpH: 8.0 T: 25°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+3nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 44-53 nMMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMpH: 8.0 T: 25°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Effect on functional cellular GR-antagonism (GRAF) in human Glucocorticoid receptor (GR) expressing cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of recombinant rat ecto-5' nucleotidase expressed in COS7 cell membranes assessed as inorganic phosphate release using AMP as substrate uM...More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+3nMpH: 8.0 T: 25°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Affinity DataIC50: 1.94E+3nMAssay Description:Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)More data for this Ligand-Target Pair
Affinity DataIC50: 1.97E+3nMpH: 8.0 T: 25°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of human TNAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.01E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair