Affinity DataKi: 0.600nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 185nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+3nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+3nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 5.10E+3nMAssay Description:Inhibitory activity of the compound against human CCR5 chemokine receptor (CCR5) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40E+3nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.40E+3nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.14E+4nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.70E+4nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Inhibitory activity of the compound against human CCR5 chemokine receptor (CCR5) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >3.50E+4nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of QNB from muscarinic M2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of QNB from muscarinic M1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of QNB from muscarinic M4 receptorMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory activity of the compound evaluated in the HCV NS3 protease activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibitory activity of the compound evaluated in the HCV NS3 protease assayMore data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Displacement of QNB from muscarinic M4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Displacement of QNB from muscarinic M2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibitory concentration against binding of [3H]spiperone to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Displacement of QNB from muscarinic M1 receptorMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of Aurora 2 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of AUR2More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair