Affinity DataKi: 37nMAssay Description:Inhibitory concentration against Mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibitory concentration against Mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Antagonistic activity against stimulation of GTP (gamma) 35 S binding by glutamate in membranes from CHO cells expressing human Metabotropic glutamat...More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]L-AP4 from rat mGluR4 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 201nMAssay Description:Inhibitory concentration against Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 224nMAssay Description:Inhibitory concentration against Glucorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 224nMAssay Description:Inhibitory concentration against Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibitory concentration against Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Displacement of [3H]quisqualate from mGluR1 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 252nMAssay Description:Inhibitory concentration against Glucorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 315nMAssay Description:Inhibitory concentration against Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Binding affinity to mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.16E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Displacement of [3H]LY341495 from rat mGluR8 expressed in BHK cellsMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKi: 2.18E+3nMAssay Description:Uncompetitive inhibition of human N-terminal His6-SUMO-tagged SIRT2 catalytic domain (43 to 356 residues) deacetylase activity expressed in Escherich...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKi: 2.22E+3nMAssay Description:Uncompetitive inhibition of human N-terminal His6-SUMO-tagged SIRT2 catalytic domain (43 to 356 residues) deacetylase activity expressed in Escherich...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Displacement of [3H]LAP4 from mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Antagonistic activity against stimulation of GTP (gamma) 35 S binding by glutamate in membranes from CHO cells expressing human Metabotropic glutamat...More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat mGluR4 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]LY341495 from rat mGluR8 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory concentration against Farnesoid X receptorMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory concentration against Farnesoid X receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat mGluR4 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Displacement of [3H]LY341495 from mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+4nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+4nMAssay Description:Displacement of [3H]quisqualate from mGluR1 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.40E+4nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 4.90E+4nMAssay Description:Binding affinity to mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Binding affinity towards mGluR1a was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: 5.30E+4nMAssay Description:Displacement of [3H]LAP4 from mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.30E+4nMAssay Description:Displacement of [3H]L-AP4 from rat mGluR4 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40E+4nMAssay Description:Binding affinity to mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40E+4nMAssay Description:Displacement of [3H]LY341495 from rat mGluR8 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+4nMAssay Description:Binding affinity to mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.90E+4nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 6.30E+4nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+4nMAssay Description:Displacement of [3H]LY341495 from rat mGluR8 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nMAssay Description:Binding affinity to mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.70E+4nMAssay Description:Displacement of [3H]quisqualate from mGluR1 receptor expressed in BHK cellsMore data for this Ligand-Target Pair