Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of C-terminal His6-tagged Phytophthora sojae race 1 recombinant ThrRS expressed in Escherichia coli BL21 (Codonplus DE3) assessed as reduc...More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of FGFR4 V550L mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of FGFR2 V564M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of wild type FGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human RET V804L mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human RET V804M mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human wild type RETMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human wild type RETMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human RET V804L mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild type FGFR1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild type FGFR4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of FGFR1 V561M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human RET V804M mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 0.910nMAssay Description:Inhibitory concentration against MMP-2More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of wild type FGFR3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Bcr-Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of FGFR3 V555M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of TRKC (unknown origin) using Ser/Thr 06 peptide as substrate incubated for 1 hr in presence of 50 uM ATP by FRET based Z'-Lyte assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of N-terminal hexahistidine tagged TRKA (485 to 795 residues) (unknown origin) expressed in Sf9 cells using Ser/Thr 06 peptide as substrat...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of TRKA G667C mutant (unknown origin) using Ser/Thr 06 peptide as substrate incubated for 1 hr in presence of 400 uM ATP by FRET based Z'-...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type KIT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal hexahistidine tagged TRKA (485 to 795 residues) (unknown origin) expressed in Sf9 cells using Ser/Thr 06 peptide as substrat...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of CD74 fused TRKA G667C mutant (unknown origin) expressed in mouse BaF3 cells assessed as inhibition of PLCgamma1 phosphorylation incubat...More data for this Ligand-Target Pair