Compile Data Set for Download or QSAR
maximum 50k data
Found 83 with Last Name = 'yamori' and Initial = 't'
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Riken

Curated by ChEMBL
LigandPNGBDBM50017721(1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ac-KRSK-MCA peptide/SAM as substrate preincubated fo...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558325(CHEMBL4746359)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425908(CHEMBL2313363)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425909(SPIRUCHOSTATIN C)
Affinity DataIC50:  0.930nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558323(CHEMBL4777615)
Affinity DataIC50:  0.960nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558327(CHEMBL4798082)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558329(CHEMBL4776416)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant PI3Kdelta HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558322(CHEMBL4754402)
Affinity DataIC50:  11nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558324(CHEMBL4796742)
Affinity DataIC50:  41nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  44nMAssay Description:Inhibition of recombinant PI3Kbeta HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant PI3Kgamma HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558325(CHEMBL4746359)
Affinity DataIC50:  55nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558328(CHEMBL4789369)
Affinity DataIC50:  92nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  109nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250101((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-car...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558326(CHEMBL4777660)
Affinity DataIC50:  184nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425908(CHEMBL2313363)
Affinity DataIC50:  240nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant HDAC2 by fluorometryMore data for this Ligand-Target Pair
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50312665(CHEMBL1088572 | Sodium 2-(2-Fluorophenyl)-6,7-meth...)
Affinity DataIC50:  314nMAssay Description:Inhibition of human PTP4A2 by enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250099((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425909(SPIRUCHOSTATIN C)
Affinity DataIC50:  320nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant HDAC1 by fluorometryMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558324(CHEMBL4796742)
Affinity DataIC50:  355nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  390nMAssay Description:Inhibition of mouse HDAC6 expressed in human 293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  390nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250101((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-car...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human recombinant HDAC2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50312665(CHEMBL1088572 | Sodium 2-(2-Fluorophenyl)-6,7-meth...)
Affinity DataIC50:  676nMAssay Description:Inhibition of human PTP4A1 by enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Keio University

Curated by ChEMBL
LigandPNGBDBM50128235(CHEMBL3628709)
Affinity DataIC50:  780nMAssay Description:Inhibition of M-CSF/sRANKL-induced mouse BMDM differentiation into osteoclast after 72 hrs by TRAP staining-based microscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250099((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...)
Affinity DataIC50:  830nMAssay Description:Inhibition of human recombinant HDAC2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558329(CHEMBL4776416)
Affinity DataIC50:  859nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50354088(CHEMBL1836142)
Affinity DataIC50:  992nMAssay Description:Inhibition of mouse HDAC6 expressed in human 293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Riken

Curated by ChEMBL
LigandPNGBDBM50017721(1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using biotinylated histone H3-derived peptide/SAM as subst...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558327(CHEMBL4798082)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558326(CHEMBL4777660)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50249973((S)-6-(Benzenecarbonylamino)-7-(biphenyl-3-ylamino...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558328(CHEMBL4789369)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50312665(CHEMBL1088572 | Sodium 2-(2-Fluorophenyl)-6,7-meth...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of human cathepsin S by enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant HDAC8 by fluorometryMore data for this Ligand-Target Pair
TargetCathepsin E(Homo sapiens (Human))
China Medical University

Curated by ChEMBL
LigandPNGBDBM50312665(CHEMBL1088572 | Sodium 2-(2-Fluorophenyl)-6,7-meth...)
Affinity DataIC50:  1.71E+3nMAssay Description:Inhibition of human cathepsin E by enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50449386(CHEMBL3126833)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in human 293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics

Curated by ChEMBL
LigandPNGBDBM50365736(CHEMBL1956189)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50120465(CHEMBL281995 | N-(2-Chloro-1H-indol-7-yl)-4-methox...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity against tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50250101((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(thiazole-5-car...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human recombinant HDAC1 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50101086(CHEMBL20684 | E-7010 | N-(2-(4-hydroxyphenylamino)...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50558322(CHEMBL4754402)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 83 total ) | Next | Last >>
Jump to: