Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Ac-KRSK-MCA peptide/SAM as substrate preincubated fo...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.75nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.930nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.960nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant PI3Kdelta HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant PI3Kbeta HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant PI3Kgamma HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 184nMAssay Description:Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant HDAC2 by fluorometryMore data for this Ligand-Target Pair
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
China Medical University
Curated by ChEMBL
China Medical University
Curated by ChEMBL
Affinity DataIC50: 314nMAssay Description:Inhibition of human PTP4A2 by enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant HDAC1 by fluorometryMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 355nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of mouse HDAC6 expressed in human 293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant HDAC2 by fluorometryMore data for this Ligand-Target Pair
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
China Medical University
Curated by ChEMBL
China Medical University
Curated by ChEMBL
Affinity DataIC50: 676nMAssay Description:Inhibition of human PTP4A1 by enzyme assayMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of M-CSF/sRANKL-induced mouse BMDM differentiation into osteoclast after 72 hrs by TRAP staining-based microscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant HDAC2 by fluorometryMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 859nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 992nMAssay Description:Inhibition of mouse HDAC6 expressed in human 293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant Set7/9 (unknown origin) expressed in Escherichia coli BL21 (DE3) using biotinylated histone H3-derived peptide/SAM as subst...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human cathepsin S by enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant HDAC8 by fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of human cathepsin E by enzyme assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in human 293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Tianjin Key Laboratory On Technologies Enabling Development Of Clinical Therapeutics And Diagnostics
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity against tubulin polymerization.More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant HDAC1 by fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against tubulin polymerization.More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair