TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Displacement of [3H]PGE4 from human EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]PGE4 from human EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]PGE4 from human EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 0.950nMAssay Description:Displacement of [3H]mazindol from cocaine binding site on Dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]PGE4 from human EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]PGE4 from human EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: >1.30nMAssay Description:Inhibition of [3H]5-HT uptake at striatal nerve endings by serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]PGE4 from human EP4 receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]PGE4 from human EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:In vitro inhibitory constant against trypsinMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair