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Found 27 with Last Name = 'arguin' and Initial = 'g'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50453241(CHEMBL4206625)
Affinity DataKi:  27nMAssay Description:Inhibition of human NPP1 using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50453240(CHEMBL4218881)
Affinity DataKi:  240nMAssay Description:Inhibition of human NPP1 using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50504513(CHEMBL4465876)
Affinity DataKi:  730nMAssay Description:Inhibition of human NPP1 expressed in COS7 cell membranes using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50504512(CHEMBL4443638)
Affinity DataKi:  940nMAssay Description:Inhibition of human NPP1 expressed in COS7 cell membranes using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50453242(CHEMBL4213959)
Affinity DataKi:  1.11E+3nMAssay Description:Inhibition of human NPP1 using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50504514(CHEMBL4450742)
Affinity DataKi:  1.28E+3nMAssay Description:Inhibition of human NPP1 expressed in COS7 cell membranes using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50504510(CHEMBL4558341)
Affinity DataKi:  2.83E+3nMAssay Description:Inhibition of human NPP1 expressed in COS7 cell membranes using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50504511(CHEMBL4545695)
Affinity DataKi:  1.63E+4nMAssay Description:Inhibition of full-length human NPP-1 expressed in baculovirus infected Sf9 cells using p-Nph5-TMP as substrate after 60 mins by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50453241(CHEMBL4206625)
Affinity DataIC50:  125nMAssay Description:Inhibition of human NPP1 using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50453240(CHEMBL4218881)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human NPP1 using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50453242(CHEMBL4213959)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human NPP1 using pNP-TMP as substrate preincubated for 3 mins followed by substrate addition measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50114076(CHEMBL3604024)
Affinity DataIC50:  1.12E+5nMAssay Description:Antagonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced increase in intracellula...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50403871(URIDINE_DIPHOSPHATE)
Affinity DataEC50:  15nMAssay Description:Agonist activity at P2Y6 receptor expressed in human 1321N1 cells assessed as inositol phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50306710(((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at P2Y6 receptor expressed in human 1321N1 cells assessed as inositol phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50421169(CHEMBL2086770)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human P2Y6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50403871(URIDINE_DIPHOSPHATE)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human P2Y6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50421168(CHEMBL2086768)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50421167(CHEMBL2086767)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50421166(CHEMBL2086766)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50421165(CHEMBL2086765)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50421164(CHEMBL2086764)
Affinity DataEC50:  2.01E+4nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50421163(CHEMBL2086763)
Affinity DataEC50:  1.12E+4nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50421162(CHEMBL2086762)
Affinity DataEC50:  4.30E+3nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50421161(CHEMBL2086761)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50403871(URIDINE_DIPHOSPHATE)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human GFP-tagged P2Y6 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 4(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human GFP-tagged P2Y4 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human GFP-tagged P2Y2 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed