TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERalpha expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Mus musculus)
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to ERbeta receptor in mouse COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Mus musculus)
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to ERalpha receptor in mouse COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERbeta expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERalpha expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERalpha expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Binding affinity to GPR30More data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity to GPR30More data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
Affinity DataIC50: 136nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 185nMAssay Description:Antagonist activity at GPR30 in human SKBr3 cells assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.72E+3nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
Affinity DataEC50: 115nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as half life for increase in intracellular calcium level by spectrofluorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
Affinity DataEC50: 294nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as half life for increase in intracellular calcium level by spectrofluorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair