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Found 37 with Last Name = 'arterburn' and Initial = 'jb'
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  0.300nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERalpha expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Mus musculus)
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50303804((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl)-3...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to ERbeta receptor in mouse COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Mus musculus)
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50303803(1-((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to ERalpha receptor in mouse COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  0.380nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERbeta expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  0.650nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM36492(E2-NMe3+)
Affinity DataKi:  1.40nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM36491(E2-COO-)
Affinity DataKi:  2nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM36493(E2-NB)
Affinity DataKi:  2.70nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM36490(E2-NH3+)
Affinity DataKi:  4.10nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  5.70nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  9nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50303803(1-((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl...)
Affinity DataKi:  11nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM36493(E2-NB)
Affinity DataKi:  16nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM36492(E2-NMe3+)
Affinity DataKi:  17nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM36490(E2-NH3+)
Affinity DataKi:  25nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM36491(E2-COO-)
Affinity DataKi:  30nMAssay Description:Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50303803(1-((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERalpha expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50324674(1-((3aS,4S,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERalpha expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50303803(1-((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl...)
Affinity DataIC50:  11nMAssay Description:Binding affinity to GPR30More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50303804((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl)-3...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to GPR30More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351257(CHEMBL1818527)
Affinity DataIC50:  127nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351253(CHEMBL1818528)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351254(CHEMBL1818529)
Affinity DataIC50:  136nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50303804((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl)-3...)
Affinity DataIC50:  185nMAssay Description:Antagonist activity at GPR30 in human SKBr3 cells assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351255(CHEMBL1818525)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM23823((2R)-2-amino-3-{[(4-methoxyphenyl)diphenylmethyl]s...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351256(CHEMBL1818526)
Affinity DataIC50:  310nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataIC50:  620nMAssay Description:Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataEC50:  1.72E+3nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351254(CHEMBL1818529)
Affinity DataEC50:  115nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM23823((2R)-2-amino-3-{[(4-methoxyphenyl)diphenylmethyl]s...)
Affinity DataEC50:  230nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351253(CHEMBL1818528)
Affinity DataEC50:  160nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50303803(1-((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as half life for increase in intracellular calcium level by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351257(CHEMBL1818527)
Affinity DataEC50:  190nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351256(CHEMBL1818526)
Affinity DataEC50:  294nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at GFP-tagged GPR30 expressed in COS7 cells assessed as half life for increase in intracellular calcium level by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
New Mexico State University

Curated by ChEMBL
LigandPNGBDBM50351255(CHEMBL1818525)
Affinity DataEC50:  600nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed