Found 454 with Last Name = 'bae' and Initial = 'ma' TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity to CypA (unknown origin) assessed as inhibition constant by isomer specific proteolysis assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Binding affinity to CypA (unknown origin) assessed as inhibition constant by isomer specific proteolysis assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Binding affinity to CypA (unknown origin) assessed as inhibition constant by isomer specific proteolysis assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity to CypA (unknown origin) assessed as inhibition constant by isomer specific proteolysis assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity to CypA (unknown origin) assessed as inhibition constant by isomer specific proteolysis assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.100nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Antagonist activity at human P2X7 receptor in expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptakeMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.200nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.400nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.800nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.870nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1.30nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human P2X7 receptor in expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptakeMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptake after 2 hrs by fluorescence ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptake after 2 hrs by fluorescence ...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antagonist activity at P2X7 in LPS/IFN gamma differentiated human THP-1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated f...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human P2X7 receptor in expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced EtBr uptake after 2 hrs by fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 4.80nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human DGAT1 expressed in human Hep3B cells incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid sc...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 5nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 5nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
