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Found 196 with Last Name = 'bajpai' and Initial = 'm'
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089369(CHEMBL3577959)
Affinity DataKi:  0.700nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089375(CHEMBL3577953)
Affinity DataKi:  1nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089374(CHEMBL3577954)
Affinity DataKi:  1nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50346208((1-isopropylpiperidin-4-yl)(4-(piperidin-1-ylmethy...)
Affinity DataKi:  1.30nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089372(CHEMBL3577956)
Affinity DataKi:  1.30nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089370(CHEMBL3577958)
Affinity DataKi:  1.5nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089368(CHEMBL3577960)
Affinity DataKi:  2nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089373(CHEMBL3577955)
Affinity DataKi:  2.5nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089378(CHEMBL3577951)
Affinity DataKi:  5nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089371(CHEMBL3577957)
Affinity DataKi:  5.40nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089377(CHEMBL3577952)
Affinity DataKi:  6nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089383(CHEMBL1707983)
Affinity DataKi:  22nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50089384(CHEMBL3577950)
Affinity DataKi:  24nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130865(CHEMBL3634853)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130760(CHEMBL3634855)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50048260(CHEMBL3315045)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant GST-tagged PDE10A using [3H]-cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130759(CHEMBL3634854)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM31592(PF-2545920 | US9138494, MP-10 | substituted pyraz...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE10A assessed as substrate hydrolysis using [3H]cAMP as substrate after 30 mins by two-step r...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130761(CHEMBL3634856)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130763(CHEMBL3634858)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048260(CHEMBL3315045)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of rat recombinant GST-tagged PDE10A using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50494753(CHEMBL3094144)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130849(CHEMBL3634744)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130850(CHEMBL3634746)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Mus musculus)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048260(CHEMBL3315045)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of mouse recombinant GST-tagged PDE10A using [3H]-cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130860(CHEMBL3634847)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130853(CHEMBL3634748)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50048261(CHEMBL3315044)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant GST-tagged PDE10A using [3H]-cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50381287(CHEMBL2019020)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]-cAMP from human recombinant PDE7AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM31596(substituted pyrazole, 13)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE10A assessed as substrate hydrolysis using [3H]cAMP as substrate after 30 mins by two-step r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130854(CHEMBL3634749)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130841(CHEMBL3634745)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130762(CHEMBL3634857)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130856(CHEMBL3634751)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130858(CHEMBL3634845)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50048258(CHEMBL3315046)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant GST-tagged PDE10A using [3H]-cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Mus musculus)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50130841(CHEMBL3634745)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of mouse PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 mins by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130851(CHEMBL3634747)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50397056(CHEMBL2171440)
Affinity DataIC50:  3nMAssay Description:Inhibition of cloned human recombinant PDE7A assessed as [3H]cAMP hydrolysis by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130840(CHEMBL3634865)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50381291(CHEMBL2019104)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]-cAMP from human recombinant PDE7AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Mus musculus)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048261(CHEMBL3315044)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of mouse recombinant GST-tagged PDE10A using [3H]-cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50130841(CHEMBL3634745)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of rat PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 mins by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50494759(CHEMBL3094141)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130855(CHEMBL3634750)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50494752(CHEMBL3094147)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048261(CHEMBL3315044)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of rat recombinant GST-tagged PDE10A using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50048262(CHEMBL3315042)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human recombinant GST-tagged PDE10A using [3H]-cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50130857(CHEMBL3634752)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Glenmark Research Centre

Curated by ChEMBL
LigandPNGBDBM50494757(CHEMBL3094139)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human recombinant PDE10A using [3H]-cAMP/[3H]-cGMP as substrate after 30 mins by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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