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Found 526 with Last Name = 'baker' and Initial = 'sr'
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173945(CHEMBL195190 | [2,2']Bithiophenyl-5-carboxylic aci...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173953(CHEMBL364069 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173956(CHEMBL370535 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50031704((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...)
Affinity DataKi:  3nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173944(5'-phenyl-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173942(CHEMBL195329 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173943(5-Phenyl-thiophene-2-carboxylic acid (1-aza-bicycl...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50231624(CHEMBL129703)
Affinity DataKi:  3.70nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173947(5-Phenyl-isothiazole-3-carboxylic acid (1-aza-bicy...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50231626(CHEMBL128013)
Affinity DataKi:  4.40nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029462(2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  5.90nMAssay Description:Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]-LTB4 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50231625(CHEMBL128067)
Affinity DataKi:  6.20nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50170587(5-Pyridin-2-yl-thiophene-2-carboxylic acid (1-aza-...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088223(CHEMBL61751 | E-2-Amino-4-(3-naphthalen-1-yl-allyl...)
Affinity DataKi:  7nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50366779(METHYLLYCACONITINE)
Affinity DataKi:  7.30nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088197(CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...)
Affinity DataKi:  8nMAssay Description:Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  8nMAssay Description:Ability of the compound to bind to Ionotropic glutamate receptor kainate (kainate 2) was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088197(CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...)
Affinity DataKi:  8nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173941(5'N-(3-pyridylmethyl)-(2'R)-spiro[4-azabicyclo[2.2...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50121539(CHEMBL3616856)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]-459477 from human recombinant mGlu2 receptor expressed in AV12 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  10nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50031704((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...)
Affinity DataKi:  10nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  10nMAssay Description:Ability of the compound to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088229(2-Amino-4-prop-2-ynyl-pentanedioic acid | CHEMBL59...)
Affinity DataKi:  11.6nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50121540(CHEMBL3616857)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-459477 from human recombinant mGlu2 receptor expressed in AV12 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036743(CHEMBL60617 | Sodium salt of 4-Ethyl-5-[6-methyl-6...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088222((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Affinity DataKi:  14nMAssay Description:Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173952(Benzo[b]thiophene-2-carboxylic acid (1-aza-bicyclo...)
Affinity DataKi:  14.6nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088222((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Affinity DataKi:  15nMAssay Description:Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088222((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Affinity DataKi:  15nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173949(5-Phenyl-thiophene-3-carboxylic acid (1-aza-bicycl...)
Affinity DataKi:  16.7nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50231631(CHEMBL128675)
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088212(2-Amino-4-but-2-enyl-pentanedioic acid(LY339180) |...)
Affinity DataKi:  21nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029452(2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  25nMAssay Description:Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]-LTB4 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50231603(CHEMBL128859)
Affinity DataKi:  25nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173951(CHEMBL194984 | N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  26.9nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50121599(CHEMBL3616858)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]-459477 from human recombinant mGlu2 receptor expressed in AV12 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088228(2-Amino-4-but-2-ynyl-pentanedioic acid | CHEMBL620...)
Affinity DataKi:  28.9nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088216(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Affinity DataKi:  30nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088203(CHEMBL301915 | E-2-Amino-4-[3-(4-bromo-phenyl)-all...)
Affinity DataKi:  30nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088216(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Affinity DataKi:  30nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  32nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088235(CHEMBL300368 | E-2-Amino-4-[3-(4-methylsulfanyl-ph...)
Affinity DataKi:  32nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataKi:  32nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 2 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029468(2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]-LTB4 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50091477((S)-2-Amino-4-cyclopentylidene-pentanedioic acid |...)
Affinity DataKi:  33nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029467(2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  36nMAssay Description:Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]-LTB4 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50231607(CHEMBL127218)
Affinity DataKi:  37nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088224(CHEMBL305346 | E-2-Amino-4-[3-(3-methoxy-phenyl)-a...)
Affinity DataKi:  40nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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