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Found 42 with Last Name = 'barbeau' and Initial = 'x'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50307347(CHEMBL1783614)
Affinity DataKi:  58nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50307126(CHEMBL4160816)
Affinity DataKi:  71nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306037(CHEMBL4163119)
Affinity DataKi:  90nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306044(CHEMBL4163923)
Affinity DataKi:  101nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50307248(CHEMBL4174875)
Affinity DataKi:  211nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50307128(CHEMBL4164216)
Affinity DataKi:  218nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306578(CHEMBL4166272)
Affinity DataKi:  231nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50307116(CHEMBL4162412)
Affinity DataKi:  242nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306038(CHEMBL4159456)
Affinity DataKi:  297nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306040(CHEMBL4174575)
Affinity DataKi:  302nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306036(CHEMBL4171038)
Affinity DataKi:  366nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306035(CHEMBL4159758)
Affinity DataKi:  465nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50307124(CHEMBL4168465)
Affinity DataKi:  699nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306708(CHEMBL4174184)
Affinity DataKi:  1.31E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306039(CHEMBL4167364)
Affinity DataKi:  1.34E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50307125(CHEMBL4168092)
Affinity DataKi:  1.84E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306945(CHEMBL4162819)
Affinity DataKi:  3.24E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50307249(CHEMBL4167667)
Affinity DataKi:  3.58E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50306946(CHEMBL4173090)
Affinity DataKi:  7.97E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  0.0300nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50545255(CHEMBL4643348)
Affinity DataIC50:  0.0400nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50168219(CHEMBL3805209)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50545254(CHEMBL4639657)
Affinity DataIC50:  2.10nMAssay Description:Irreversible inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50193084(CHEMBL3910182)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50193082(CHEMBL3953180)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50193083(CHEMBL3981927)
Affinity DataIC50:  17nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)
Affinity DataIC50:  24nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50373700(CHEMBL410242)
Affinity DataIC50:  27nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50:  28nMAssay Description:Reversible inhibition of steroid sulfatase in human JEG3 cells using [3H] E1S as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50366532(CHEMBL518966)
Affinity DataIC50:  45nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50400509(CHEMBL2203397)
Affinity DataIC50:  68nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50545253(CHEMBL4632735)
Affinity DataIC50:  69nMAssay Description:Reversible inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50400509(CHEMBL2203397)
Affinity DataIC50:  97nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50495475(CHEMBL3108979)
Affinity DataIC50:  153nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50495474(CHEMBL3108980)
Affinity DataIC50:  172nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50400510(CHEMBL2203399)
Affinity DataIC50:  430nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50078673(CHEMBL3415436)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of 17 beta-HSD1 in human T47D cells assessed as inhibition of transformation of [14C]E1 to [14C]E2 after overnight incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50373700(CHEMBL410242)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50400509(CHEMBL2203397)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50078674(CHEMBL3415431)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of 17 beta-HSD1 in human T47D cells assessed as inhibition of transformation of [14C]E1 to [14C]E2 after overnight incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  7.60E+3nMAssay Description:Reversible inhibition of steroid sulfatase in human JEG3 cells using [3H] E1S as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed