Affinity DataKi: 20nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataKi: 423nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 720nMAssay Description:Time dependent inhibition of CYP2D6 in human liver microsomes assessed as equilibrium inhibition binding constant in presence of NADPH by LC-MS/MS an...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataKi: 1.17E+3nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataKi: 2.36E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 2.78E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.13E+3nMAssay Description:Time dependent inhibition of CYP2D6 in human liver microsomes assessed as equilibrium inhibition binding constant in presence of NADPH by LC-MS/MS an...More data for this Ligand-Target Pair
Affinity DataKi: 3.17E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 4.90E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataKi: >8.00E+3nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataKi: 8.82E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Affinity DataKi: 9.36E+4nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: <0.0300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: <0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: <0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Amri
Curated by ChEMBL
Amri
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair