Found 50 with Last Name = 'barrett' and Initial = 'ag' TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2/cyclinE assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:CDK9 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:Human CDK9/cycK (Promega, V4104).CDKtide (SignalChem, C06-58).Ass...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of CDK1/cyclinB1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 34nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of CDK9/cyclinT assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK2/cyclinE assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:CDK9 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:Human CDK9/cycK (Promega, V4104).CDKtide (SignalChem, C06-58).Ass...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:CDK9 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:Human CDK9/cycK (Promega, V4104).CDKtide (SignalChem, C06-58).Ass...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:CDK9 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:Human CDK9/cycK (Promega, V4104).CDKtide (SignalChem, C06-58).Ass...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:CDK9 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:Human CDK9/cycK (Promega, V4104).CDKtide (SignalChem, C06-58).Ass...More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Inhibition of CDK9/cyclinT assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of CK1More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IRRMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of DYRK1AMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CDK1/cyclinB1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:CDK2 IC50 Materials and solutions:HEPES (Sigma, H3375).Sodium orthovanadate (Sigma, 450243).DTT (Sigma).MgCl2 (Sigma, M1028).PEG-20000 (Sigma, 95172)...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of CAMKKbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
Affinity DataIC50: 3.73E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of CDK4/cyclinD1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CDK4/cyclinD1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of CDK6/cyclinD1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of CDK6/cyclinD1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
