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Found 93 with Last Name = 'bastian' and Initial = 'm'
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268316(CHEMBL4080186)
Affinity DataKi:  0.470nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268309(CHEMBL4088060)
Affinity DataKi:  0.590nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268309(CHEMBL4088060)
Affinity DataKi:  0.710nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268317(CHEMBL4076356)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268316(CHEMBL4080186)
Affinity DataKi:  19nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268317(CHEMBL4076356)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268310(CHEMBL4069479)
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268311(CHEMBL4104422)
Affinity DataKi:  190nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268311(CHEMBL4104422)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50268310(CHEMBL4069479)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323257(1-methyl-6-(4-(pyridin-2-ylmethoxy)-3-(trifluorome...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323247(6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323087(2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9H-purine-6...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of cathepsin S-mediated proteolytic cleavage of MHC2 associated invariant chain in mouse splenocytes assessed as accumulation of lip10 by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323253(1-methyl-6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323248(1-methyl-6-(4-(2-(3-oxopiperazin-1-yl)ethoxy)-3-(t...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323250(1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323250(1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323245(1-methyl-6-(4-(3-(4-methylpiperazin-1-yl)propoxy)-...)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323255(1-methyl-6-(4-(pyridin-4-ylmethoxy)-3-(trifluorome...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323254(1-methyl-6-(4-(2-(6-methylpyridin-2-yl)ethoxy)-3-(...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323256(1-methyl-6-(4-(pyridin-3-ylmethoxy)-3-(trifluorome...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323251(1-methyl-6-(4-(piperidin-4-ylmethoxy)-3-(trifluoro...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323257(1-methyl-6-(4-(pyridin-2-ylmethoxy)-3-(trifluorome...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323258(6-(4-(3-hydroxypropyl)-3-(trifluoromethyl)phenyl)-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323271(6-(4-ethoxy-3-(trifluoromethyl)phenyl)-1H-imidazo[...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323261(1-(3-(dimethylamino)propyl)-6-(4-ethoxy-3-(trifluo...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323246(1-methyl-6-(4-(3-(pyrrolidin-1-yl)propoxy)-3-(trif...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50322925(6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(trifluoro...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323263(1-(2-(dimethylamino)ethyl)-6-(4-ethoxy-3-(trifluor...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323262(6-(4-ethoxy-3-(trifluoromethyl)phenyl)-1-(3-morpho...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323264(6-(4-ethoxy-3-(trifluoromethyl)phenyl)-1-(2-morpho...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323260(6-(4-ethoxy-3-(trifluoromethyl)phenyl)-1-methyl-1H...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323247(6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323268(6-(4-(3-hydroxypropoxy)-3-(trifluoromethyl)phenyl)...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323259(6-(4-(2-hydroxyethyl)-3-(trifluoromethyl)phenyl)-1...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323247(6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...)
Affinity DataIC50:  84nMAssay Description:Inhibition of cathepsin S-mediated proteolytic cleavage of MHC2 associated invariant chain in human JY cells assessed as accumulation of lip10 by Wes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323246(1-methyl-6-(4-(3-(pyrrolidin-1-yl)propoxy)-3-(trif...)
Affinity DataIC50:  89nMAssay Description:Inhibition of cathepsin S-mediated proteolytic cleavage of MHC2 associated invariant chain in human JY cells assessed as accumulation of lip10 by Wes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323266(6-(4-(ethylamino)-3-(trifluoromethyl)phenyl)-1H-im...)
Affinity DataIC50:  105nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323245(1-methyl-6-(4-(3-(4-methylpiperazin-1-yl)propoxy)-...)
Affinity DataIC50:  106nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323270(6-(4-(2-hydroxyethoxy)-3-(trifluoromethyl)phenyl)-...)
Affinity DataIC50:  145nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323250(1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...)
Affinity DataIC50:  178nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323269(6-(4-propoxy-3-(trifluoromethyl)phenyl)-1H-imidazo...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323249(6-(4-(2-(dimethylamino)ethoxy)-3-(trifluoromethyl)...)
Affinity DataIC50:  209nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323251(1-methyl-6-(4-(piperidin-4-ylmethoxy)-3-(trifluoro...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323261(1-(3-(dimethylamino)propyl)-6-(4-ethoxy-3-(trifluo...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323254(1-methyl-6-(4-(2-(6-methylpyridin-2-yl)ethoxy)-3-(...)
Affinity DataIC50:  267nMAssay Description:Inhibition of cathepsin S-mediated proteolytic cleavage of MHC2 associated invariant chain in human JY cells assessed as accumulation of lip10 by Wes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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