Affinity DataKi: 0.0700nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nM ΔG°: -54.8kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of human fXa assessed as inhibition constant using Cbz-D-Arg-Gly-L-Arg-pNA as substrate preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -52.3kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.4kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 6(Homo sapiens (Human))
University Of Gdansk
Curated by ChEMBL
University Of Gdansk
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair