Affinity DataKi: 0.00143nMAssay Description:Inhibition of human cathepsin K using Z-Leu-Arg-AMC fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University Of Leipzig
Curated by ChEMBL
University Of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.00200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00420nMAssay Description:Inhibition of human cathepsin K using Z-Leu-Arg-AMC fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University Of Leipzig
Curated by ChEMBL
University Of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.00600nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0110nMAssay Description:Inhibition of human cathepsin K using Z-Leu-Arg-AMC fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University Of Leipzig
Curated by ChEMBL
University Of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University Of Leipzig
Curated by ChEMBL
University Of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Affinity DataKi: 0.0631nMAssay Description:Effect on pancreatic polypeptide-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.0870nMAssay Description:Kinetic parameter (Ki 1/min) was evaluated for the inactivation of cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity for opioid receptor like type, human Opioid receptor like 1 expressed in membrane homogenates of COS-1 or CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Arg-AMC fluorogenic substrate fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.176nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Arg-AMC fluorogenic substrate fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.208nMAssay Description:Kinetic parameter (Ki 1/min) was evaluated for the inactivation of papainMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-AVP from human V1A receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.406nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA chromogenic substrate fluorogenic substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.459nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA chromogenic substrate fluorogenic substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Displacement of [3H]AVP from V1A receptor in Wistar rat liver membranes incubated for 60 mins by microplate scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Displacement of [3H]-AVP from human V2 receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Smithkline Beecham Pharmaceuticals
Affinity DataKi: 0.600nM EC50: 1nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University Of Leipzig
Curated by ChEMBL
University Of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [125I]-His-ghrelin from human ghrelin receptor expressed in COS7 cells incubated for 75 mins by scintillation counting based assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.777nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Arg-AMC fluorogenic substrate fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Smithkline Beecham Pharmaceuticals
Affinity DataKi: 1nM EC50: 4nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Smithkline Beecham Pharmaceuticals
Affinity DataKi: 1nM EC50: 30nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Smithkline Beecham Pharmaceuticals
Affinity DataKi: 1nM EC50: 2nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Smithkline Beecham Pharmaceuticals
Affinity DataKi: 1nM EC50: 4nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Smithkline Beecham Pharmaceuticals
Affinity DataKi: 1nM EC50: 45nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human MCF7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of human cathepsin K using Z-Leu-Arg-AMC fluorogenic substrate incubated for 60 minsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
Federal Institute of Technology of Zurich
Curated by PDSP Ki Database
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Smithkline Beecham Pharmaceuticals
Affinity DataKi: 1.5nM EC50: 70nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University Of Leipzig
Curated by ChEMBL
University Of Leipzig
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair