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Found 114 with Last Name = 'berlove' and Initial = 'd'
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066059(1,3-Bis-(4-sec-butyl-phenyl)-tetrahydro-pyrimidin-...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066062(1,3-Bis-(4-sec-butyl-phenyl)-imidazolidin-2-yliden...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066417(CHEMBL112806 | N-(4-Benzyloxy-phenyl)-N'-(4-tert-b...)
Affinity DataIC50:  110nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066427(CHEMBL109210 | N,N'-Bis-(4-butyl-phenyl)-guanidine)
Affinity DataIC50:  130nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066420(CHEMBL112132 | N-(4-Benzyloxy-phenyl)-N'-(4-butyl-...)
Affinity DataIC50:  140nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066423(CHEMBL326502 | N,N'-Bis-(4-butoxy-phenyl)-guanidin...)
Affinity DataIC50:  190nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066066((S)-1-[4-(Benzothiazol-2-yl-methyl-amino)-piperidi...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066425(CHEMBL112515 | N,N'-Bis-(4-phenoxy-phenyl)-guanidi...)
Affinity DataIC50:  430nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066067(2-(4-tert-Butyl-phenyl)-6-isopropyl-3,4-dihydro-2H...)
Affinity DataIC50:  460nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010754(CHEMBL81626 | N,N'-Bis-(4-isopropyl-phenyl)-guanid...)
Affinity DataIC50:  460nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107034(CHEMBL108347 | N-(4-Butoxy-benzoyl)-N'-(4-phenyl-b...)
Affinity DataIC50:  560nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066069(CHEMBL103284 | N-(4-tert-Butyl-benzyl)-N-(4-sec-bu...)
Affinity DataIC50:  620nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107034(CHEMBL108347 | N-(4-Butoxy-benzoyl)-N'-(4-phenyl-b...)
Affinity DataIC50:  630nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066428(CHEMBL326774 | N-Acenaphthen-5-yl-N'-(4-sec-butyl-...)
Affinity DataIC50:  680nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107029(CHEMBL108727 | N-(4-Ethoxy-benzoyl)-N'-(4-phenyl-b...)
Affinity DataIC50:  760nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066052((3-sec-Butyl-phenyl)-[1-(4-sec-butyl-phenyl)-imida...)
Affinity DataIC50:  780nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066057(CHEMBL110909 | CHEMBL320199 | N,N'-Bis-(4-sec-buty...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066057(CHEMBL110909 | CHEMBL320199 | N,N'-Bis-(4-sec-buty...)
Affinity DataIC50:  800nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107043(CHEMBL321883 | N-(4-Methoxy-benzoyl)-N'-(4-phenyl-...)
Affinity DataIC50:  820nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066419(CHEMBL326741 | N,N'-Bis-(4-hexyl-phenyl)-guanidine)
Affinity DataIC50:  830nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066424(CHEMBL331126 | N,N'-Bis-(4-phenylsulfanyl-phenyl)-...)
Affinity DataIC50:  840nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066422(CHEMBL326130 | N,N'-Bis-biphenyl-4-yl-guanidine)
Affinity DataIC50:  850nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107032(CHEMBL110572 | N-(Naphthalene-1-carbonyl)-N'-(4-ph...)
Affinity DataIC50:  860nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066060(CHEMBL545504 | N,N'-Bis-(4-sec-butyl-phenyl)-N,N'-...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107029(CHEMBL108727 | N-(4-Ethoxy-benzoyl)-N'-(4-phenyl-b...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107031(CHEMBL108728 | N-(4-Methyl-benzoyl)-N'-(4-phenyl-b...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107030(CHEMBL106459 | N-(2-Methyl-benzoyl)-N'-(4-phenyl-b...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010736(CHEMBL78083 | N,N'-Bis-(4-ethyl-phenyl)-guanidine)
Affinity DataIC50:  1.39E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107046(CHEMBL110164 | N-(4-Phenyl-butyl)-N'-(3,4,5-trimet...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107039(CHEMBL109012 | N-(2,3-Dichloro-benzoyl)-N'-(4-phen...)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107046(CHEMBL110164 | N-(4-Phenyl-butyl)-N'-(3,4,5-trimet...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066421(CHEMBL320340 | N,N'-Bis-(4-tert-butyl-phenyl)-guan...)
Affinity DataIC50:  1.54E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066068(CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...)
Affinity DataIC50:  1.64E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066068(CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...)
Affinity DataIC50:  1.64E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107030(CHEMBL106459 | N-(2-Methyl-benzoyl)-N'-(4-phenyl-b...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107045(CHEMBL421032 | N-[2-(5-Methoxy-1H-indol-3-yl)-ethy...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107045(CHEMBL421032 | N-[2-(5-Methoxy-1H-indol-3-yl)-ethy...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066429(CHEMBL325215 | N-(4-Butoxy-phenyl)-N'-[4-(4-hydrox...)
Affinity DataIC50:  1.78E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066061(1-(4-sec-Butyl-phenyl)-5-(4-isopropyl-phenyl)-imid...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107020(CHEMBL105782 | N-(4-Methyl-benzoyl)-N'-(3,4,5-trim...)
Affinity DataIC50:  1.92E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107050(CHEMBL107394 | N-(4-Isopropyl-phenyl)-N'-(4-methyl...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107035(CHEMBL320332 | N-[2-(4-Chloro-phenyl)-ethyl]-N'-(4...)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107025(CHEMBL106351 | N-(4-Isopropoxy-phenyl)-N'-(4-methy...)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107043(CHEMBL321883 | N-(4-Methoxy-benzoyl)-N'-(4-phenyl-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107037(CHEMBL106610 | N-(4-Methyl-benzoyl)-N'-(5-phenyl-p...)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107038(CHEMBL108361 | N-(4-Phenyl-butyl)-N'-(thiophene-2-...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107051(CHEMBL108627 | N-(4-Methyl-benzoyl)-N'-naphthalen-...)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066430(2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phe...)
Affinity DataIC50:  2.55E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Cenes Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107044(CHEMBL107354 | N-(4-Methyl-benzoyl)-N'-phenethyl-g...)
Affinity DataIC50:  2.66E+3nMAssay Description:Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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