Found 2137 with Last Name = 'bhat' and Initial = 'a' TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 0.165nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M2 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2 [A65S,N67Q,E69T,I91L,F131V,K170E,L204A](Homo sapiens (Human))
University of Florida
University of Florida
Affinity DataKi: 0.200nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
3D Structure (crystal)TargetCarbonic anhydrase 2 [A65S,N67Q,E69T,I91L,F131V,K170E,L204A](Homo sapiens (Human))
University of Florida
University of Florida
Affinity DataKi: 0.200nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of rat neutrophil 5- Lipoxygenase (5-LO)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 0.543nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M3 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 0.594nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 0.881nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 0.922nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Aromatase inhibitor potency as iron-binding-related type II difference spectrumMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of rat neutrophil 5- Lipoxygenase (5-LO),More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.29nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.32nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.39nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M4 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.44nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M2 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.49nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M4 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.54nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M2 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 1.59nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Ability to inhibit U-46,619-induced contraction of isolated strips of rabbit thoracic aorta, which is the measure of thromboxane receptor antagonismMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 2.18nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M3 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Antagonist activity at recombinant rat P2X7 expressed in human 1321N1 cells assessed as inhibition of BzATP-induced calcium flux preincubated for 30 ...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of Phosphodiesterase 2 from pig coronary arteryMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 2.36nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:CA-catalyzed CO2 hydration activity methods were published previously by Cornelio et al. as part of a larger series of benzenesulfonamide-based inhib...More data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 3.12nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M3 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.36nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:In vitro binding affinity towards alpha-2B adrenergic receptor of rat neonatal lung in radioligand binding assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 4.25nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M3 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-A-804598 from recombinant rat P2X7 expressed in human 1321N1 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-A-804598 from recombinant human P2X7 expressed in human 1321N1 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataKi: 5.38nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M2 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
