TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Inhibitory activity against beta-glucosidase of sweet almondMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataKi: 4.30E+4nMAssay Description:Non-competitive inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated fo...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataKi: 4.84E+4nMAssay Description:Competitive inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated for 15...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 2...More data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 20 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using methylated H3K4peptide as substrate incubated for 15 mins prior to substrate...More data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex...More data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 20 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair