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Found 929 with Last Name = 'bottini' and Initial = 'n'
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataKi:  110nMAssay Description:Competitive inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50393461(CHEMBL2159938)
Affinity DataKi:  2.16E+3nMAssay Description:Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataKi:  2.90E+3nMAssay Description:Competitive inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50393496(CHEMBL2159935)
Affinity DataKi:  3.07E+3nMAssay Description:Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50393463(CHEMBL2159940)
Affinity DataKi:  8.07E+3nMAssay Description:Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50393461(CHEMBL2159938)
Affinity DataKi:  1.07E+4nMAssay Description:Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50393462(CHEMBL2159939)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM46264(3-[2-azaspiro[5.5]undecan-2-yl-(1-cyclopentyl-1,2,...)
Affinity DataKi:  1.25E+4nMAssay Description:Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50393496(CHEMBL2159935)
Affinity DataKi:  1.76E+4nMAssay Description:Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50393462(CHEMBL2159939)
Affinity DataKi:  2.13E+4nMAssay Description:Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50393463(CHEMBL2159940)
Affinity DataKi:  2.39E+4nMAssay Description:Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataKi:  3.39E+4nMAssay Description:Inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM46264(3-[2-azaspiro[5.5]undecan-2-yl-(1-cyclopentyl-1,2,...)
Affinity DataKi:  3.81E+4nMAssay Description:Noncompetitive inhibition of LYP expressed in Escherichia coli BL21 using increasing levels of ARLIED-NEpYTAREG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576941(CHEMBL4875137)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576927(CHEMBL4856707)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576940(CHEMBL4857535)
Affinity DataIC50:  83nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576928(CHEMBL4855952)
Affinity DataIC50:  87nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576921(CHEMBL4874911)
Affinity DataIC50:  104nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576933(CHEMBL4848127)
Affinity DataIC50:  106nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576932(CHEMBL4873827)
Affinity DataIC50:  117nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576929(CHEMBL4859307)
Affinity DataIC50:  119nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576930(CHEMBL4858034)
Affinity DataIC50:  147nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576924(CHEMBL4861843)
Affinity DataIC50:  171nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  171nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576931(CHEMBL4870698)
Affinity DataIC50:  239nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576919(CHEMBL4847980)
Affinity DataIC50:  239nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576934(CHEMBL4868378)
Affinity DataIC50:  245nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50:  250nMAssay Description:Reversible inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50:  259nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 294) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50:  259nMAssay Description:Reversible inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50:  259nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436360(CHEMBL2396723)
Affinity DataIC50:  259nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436363(CHEMBL2396720)
Affinity DataIC50:  263nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576926(CHEMBL4857590)
Affinity DataIC50:  288nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436364(CHEMBL2396717)
Affinity DataIC50:  300nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 294) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436364(CHEMBL2396717)
Affinity DataIC50:  300nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576920(CHEMBL4852414)
Affinity DataIC50:  306nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436362(CHEMBL2396721)
Affinity DataIC50:  310nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant LMWPTP (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50576925(CHEMBL4846731)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant FAP-1 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  470nMAssay Description:Inhibition of recombinant PTPbeta (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533129(N-(2-cyanoethyl)(4-{4-[(3- piperidylpropyl)amino](...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533135(US10626094, Example I65 | US11220486, Compound I65...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533136(N-[2-(dimethylamino)ethyl](4-{4-[(3- piperidylprop...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533137(N-(3-hydroxypropyl)(4-{4-[(3- piperidylpropyl)amin...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533141(N,N-diethyl(4-{4-[(3-piperidylpropyl)amino](2- qui...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533144(4-{4-[(3-piperidylpropyl)amino]-2- quinolyl}benzam...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533148((2-benzo[b]thiophen-6-yl(4-quinolyl))(3- piperidyl...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM533151(2-fluoro-4-{4-[(3-piperidylpropyl)amino](2- quinol...)
Affinity DataIC50:  500nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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