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Found 30 with Last Name = 'bouckaert' and Initial = 'c'
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50369774(SEPIMOSTAT MESYLATE | Sepimostat)
Affinity DataKi:  21nMAssay Description:Non-competitive inhibition of factor 12a (unknown origin) using BQGR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50369774(SEPIMOSTAT MESYLATE | Sepimostat)
Affinity DataKi:  97nMAssay Description:Competitive inhibition of trypsin (unknown origin) using BFSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataKi:  105nMAssay Description:Inhibition of human factor 12a using chromogenic substrate by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50287780((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  230nMAssay Description:Inhibition of human factor 12a using H-D-Pro-Phe-Arg-pNa as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50556155(CHEMBL4740892)
Affinity DataKi:  800nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50104435(4-(6-Guanidino-hexanoyloxy)-benzoic acid ethyl est...)
Affinity DataKi:  2.92E+3nMAssay Description:Inhibition of human factor 12a using chromogenic substrate by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50556154(CHEMBL4749845)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50328697((R)-5-guanidino-N-(2-((S)-5-guanidino-1-oxo-1-(thi...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human factor 12a using Z-D-Arg-Gly-Arg-pNA as substrate preincubated for 5 mins followed by substrate addition by absorbance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50146944(CHEMBL3765536)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human factor 12a using S-2302 as substrate assessed as para-nitroaniline release preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50180541(4-guanidinophenyl 6-(chloromethyl)-2-oxo-2H-chrome...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human factor 12aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50146992(CHEMBL3763881)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human factor 12a using S-2302 as substrate assessed as para-nitroaniline release preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50146945(CHEMBL3763678)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human factor 12a using S-2302 as substrate assessed as para-nitroaniline release preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50556153(CHEMBL4743471)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of factor 12a (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM23548(3-Carboxamide-coumarin deriv., 44 | 8-bromo-6-chlo...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human factor 12a using S-2302 as substrate assessed as para-nitroaniline release preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50146947(CHEMBL3764790)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human factor 12a using S-2302 as substrate assessed as para-nitroaniline release preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50146946(CHEMBL3763449)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of human factor 12a using S-2302 as substrate assessed as para-nitroaniline release preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50556157(CHEMBL4753701)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of human factor 12aMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50556156(CHEMBL4794762)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of human factor 12aMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457615(CHEMBL226584)
Affinity DataEC50:  1.78E+5nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457614(CHEMBL4202524)
Affinity DataEC50:  14nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457618(CHEMBL4206883)
Affinity DataEC50:  4.03E+5nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457616(CHEMBL4218628)
Affinity DataEC50:  1.26nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457619(CHEMBL2441066)
Affinity DataEC50:  9.12E+3nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457619(CHEMBL2441066)
Affinity DataEC50:  9.06E+3nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457618(CHEMBL4206883)
Affinity DataEC50:  4.07E+5nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457617(CHEMBL4206371)
Affinity DataEC50:  4.90E+4nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457614(CHEMBL4202524)
Affinity DataEC50:  14.5nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457616(CHEMBL4218628)
Affinity DataEC50:  1.30nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457615(CHEMBL226584)
Affinity DataEC50:  1.76E+5nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457617(CHEMBL4206371)
Affinity DataEC50:  4.82E+4nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed