Compile Data Set for Download or QSAR
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Found 145 with Last Name = 'brill' and Initial = 'er'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156552(4-(2-((R)-2-((S,E)-3-hydroxy-4-(3-(methoxymethyl)p...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142480((E)-7-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)-3-hydroxy-o...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156551(4-{2-[(2S)-2-[(3R)-3-[3-(4-chloro-2-methylphenyl)p...)
Affinity DataKi:  0.940nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156553(4-(2-((R)-2-((S,E)-5-cyclobutyl-3-hydroxypent-1-en...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142482(7-{(R)-2-[(E)-(S)-3-Hydroxy-4-(3-trifluoromethyl-p...)
Affinity DataKi:  1.60nMAssay Description:Agonist activity against recombinant prostanoid EP4 receptor stably transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142476(7-{(R)-2-[(E)-3-(4'-Chloro-2'-methyl-biphenyl-3-yl...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156554(4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142474(7-[(R)-2-((E)-(S)-4-Cyclobutyl-3-hydroxy-but-1-eny...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142481(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142481(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142480((E)-7-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)-3-hydroxy-o...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity was determined against prostanoid EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142492(7-{(R)-2-[(E)-3-Hydroxy-3-(4'-hydroxy-2'-methyl-bi...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50125417(7-[(R)-2-((E)-3-Hydroxy-4-phenyl-but-1-enyl)-5-oxo...)
Affinity DataKi:  6.10nMAssay Description:Agonist activity against recombinant prostanoid EP4 receptor stably transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142493(7-{(R)-2-[(E)-3-(2'-Chloro-biphenyl-3-yl)-3-hydrox...)
Affinity DataKi:  6.20nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142480((E)-7-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)-3-hydroxy-o...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity was determined against prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156548(5-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156555(2-(4-((R)-2-((S,E)-3-hydroxy-4-(3-(trifluoromethyl...)
Affinity DataKi:  7nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142489(7-{(S)-2-[(R)-3-Hydroxy-3-(3-trifluoromethyl-pheny...)
Affinity DataKi:  7.40nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142477(7-[(R)-2-((E)-(S)-4-Cyclohexyl-3-hydroxy-but-1-eny...)
Affinity DataKi:  7.5nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142480((E)-7-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)-3-hydroxy-o...)
Affinity DataKi:  8nMAssay Description:Binding affinity was determined against prostanoid EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142484(7-{(S)-2-[(R)-3-Hydroxy-3-(4'-hydroxy-2'-methyl-bi...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142490(7-{(R)-2-[(E)-3-Hydroxy-3-(5-trifluoromethyl-furan...)
Affinity DataKi:  10nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50125409(7-{(R)-2-[(E)-3-Hydroxy-3-(1-phenyl-cyclopropyl)-p...)
Affinity DataKi:  12nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142488(7-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)phen...)
Affinity DataKi:  16nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156549(4-(2-((S)-2-((S)-3-hydroxyoctyl)-5-oxopyrrolidin-1...)
Affinity DataKi:  17nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156546(4-(2-((S)-2-((S)-5-cyclobutyl-3-hydroxypentyl)-5-o...)
Affinity DataKi:  18nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142486(7-{(R)-2-[(E)-3-Hydroxy-3-(3-phenoxy-phenyl)-prope...)
Affinity DataKi:  32nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156549(4-(2-((S)-2-((S)-3-hydroxyoctyl)-5-oxopyrrolidin-1...)
Affinity DataKi:  35nMAssay Description:Binding affinity to human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156553(4-(2-((R)-2-((S,E)-5-cyclobutyl-3-hydroxypent-1-en...)
Affinity DataKi:  75nMAssay Description:Binding affinity to human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)
Affinity DataKi:  130nMAssay Description:Binding affinity to human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142479(7-{(R)-2-[(E)-3-Hydroxy-3-(3-trifluoromethyl-pheny...)
Affinity DataKi:  140nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156546(4-(2-((S)-2-((S)-5-cyclobutyl-3-hydroxypentyl)-5-o...)
Affinity DataKi:  220nMAssay Description:Binding affinity to human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142478(7-[(R)-2-((E)-3-Biphenyl-3-yl-3-hydroxy-propenyl)-...)
Affinity DataKi:  360nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142487(7-{(R)-2-[(E)-3-(4'-Chloro-biphenyl-3-yl)-3-hydrox...)
Affinity DataKi:  390nMAssay Description:Agonist activity against recombinant prostanoid EP4 receptor stably transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142475(7-{(R)-2-[(E)-3-(3'-Chloro-biphenyl-3-yl)-3-hydrox...)
Affinity DataKi:  420nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156556(2-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)
Affinity DataKi:  530nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156550(3-(3-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)
Affinity DataKi:  900nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156554(4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity to human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142485(7-[(R)-2-((E)-3-Hydroxy-3-phenyl-propenyl)-5-oxo-p...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156552(4-(2-((R)-2-((S,E)-3-hydroxy-4-(3-(methoxymethyl)p...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity to human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142481(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity was determined against prostanoid EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156548(5-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)
Affinity DataKi:  3.70E+3nMAssay Description:Binding affinity to human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142487(7-{(R)-2-[(E)-3-(4'-Chloro-biphenyl-3-yl)-3-hydrox...)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity was determined against prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142481(7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrr...)
Affinity DataKi:  4.50E+3nMAssay Description:Binding affinity was determined against prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156554(4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrro...)
Affinity DataKi:  4.70E+3nMAssay Description:Binding affinity to human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142490(7-{(R)-2-[(E)-3-Hydroxy-3-(5-trifluoromethyl-furan...)
Affinity DataKi:  4.90E+3nMAssay Description:Binding affinity was determined against prostanoid EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156551(4-{2-[(2S)-2-[(3R)-3-[3-(4-chloro-2-methylphenyl)p...)
Affinity DataKi:  5.10E+3nMAssay Description:Binding affinity to human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity to human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142491(7-{(R)-2-[(E)-3-Hydroxy-4-(3-trifluoromethyl-pheny...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity was determined against prostanoid EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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