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Found 194 with Last Name = 'briner' and Initial = 'k'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186127(CHEMBL378408 | N-[(R)-2-{4-[2-(acetyl-ethyl-amino)...)
Affinity DataKi:  2nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186127(CHEMBL378408 | N-[(R)-2-{4-[2-(acetyl-ethyl-amino)...)
Affinity DataKi:  3nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186127(CHEMBL378408 | N-[(R)-2-{4-[2-(acetyl-ethyl-amino)...)
Affinity DataKi:  3nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186121((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(1-cyclopentyl-...)
Affinity DataKi:  4nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186131((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(1-cyclohexyl-2...)
Affinity DataKi:  4nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186863(CHEMBL379497 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186128(CHEMBL209990 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...)
Affinity DataKi:  5nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186125(CHEMBL377825 | N-((R)-3-(4-chlorophenyl)-1-(4-(3-c...)
Affinity DataKi:  5nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186128(CHEMBL209990 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...)
Affinity DataKi:  5nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177564(CHEMBL380540 | N-((R)-3-(4-chlorophenyl)-1-(4-(2-(...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186124(CHEMBL410087 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...)
Affinity DataKi:  6nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186124(CHEMBL410087 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...)
Affinity DataKi:  6nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177560(CHEMBL206042 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-(...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177560(CHEMBL206042 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-(...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186868(CHEMBL213340 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-...)
Affinity DataKi:  6.80nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186138(CHEMBL425609 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...)
Affinity DataKi:  7nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177563(CHEMBL380855 | N-((R)-3-(4-chlorophenyl)-1-(4-(2-(...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177557(CHEMBL380365 | N-((R)-3-(4-chlorophenyl)-1-(4-(2-(...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186122(CHEMBL377313 | N-((R)-3-(4-chlorophenyl)-1-(4-(3-c...)
Affinity DataKi:  10nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186120(CHEMBL380391 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-(...)
Affinity DataKi:  12nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186874(CHEMBL376999 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186862(CHEMBL211260 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186135((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(3-cyclohexyl-1...)
Affinity DataKi:  13nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186119((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(1-cycloheptyl-...)
Affinity DataKi:  13nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186133(3,4-Dihydro-1H-isoquinoline-2-carboxylic acid ((R)...)
Affinity DataKi:  14nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174056(CHEMBL381015 | Diethyl-[(S)-2-(2-fluoro-phenyl)-2-...)
Affinity DataKi:  14nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50139027((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataKi:  14nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186865(CHEMBL211202 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(1-...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177565(CHEMBL380858 | N-((R)-3-(4-chlorophenyl)-1-(4-(2-(...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186132(CHEMBL378411 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...)
Affinity DataKi:  18nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186132(CHEMBL378411 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...)
Affinity DataKi:  18nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186126(CHEMBL379051 | N-((R)-3-(4-chlorophenyl)-1-(4-(2,6...)
Affinity DataKi:  18nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177561((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamin...)
Affinity DataKi:  20nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174055(CHEMBL198379 | Diethyl-[2-(2-fluoro-phenyl)-2-(4-m...)
Affinity DataKi:  20nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50139046(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataKi:  24nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186134(CHEMBL209559 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-c...)
Affinity DataKi:  26nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50139032(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataKi:  27nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186869(CHEMBL375388 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-...)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186861(CHEMBL213940 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50139027((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataKi:  34nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186130(CHEMBL211078 | N-((R)-3-(4-chlorophenyl)-1-(4-(dic...)
Affinity DataKi:  35nMAssay Description:Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50139043(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataKi:  35nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186864(CHEMBL373735 | N-[(R)-2-[4-(1-acetyl-4-isobutyl-pi...)
Affinity DataKi:  38nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174050(CHEMBL365184 | Diethyl-[2-(4-methyl-piperazin-1-yl...)
Affinity DataKi:  40nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174062(CHEMBL371896 | Diethyl-[2-(4-methyl-piperazin-1-yl...)
Affinity DataKi:  40nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177561((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamin...)
Affinity DataKi:  41nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186871(CHEMBL211032 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-...)
Affinity DataKi:  42nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186867(CHEMBL378415 | N-[(R)-2-[4-(4-benzyl-1-methyl-pipe...)
Affinity DataKi:  44nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50186875(CHEMBL375389 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(1-...)
Affinity DataKi:  47nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50174045(CHEMBL373042 | Diethyl-[(R)-2-(4-methyl-piperazin-...)
Affinity DataKi:  50nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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