Found 135 with Last Name = 'buhrlage' and Initial = 'sj' TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Competitive inhibition of UCHL1 in human H1299 cells using Ub-AMC substrateMore data for this Ligand-Target Pair
Affinity DataIC50: <0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: <0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: <0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: <0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: <0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: <0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: <0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 1.38nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-Rh110 substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.61nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 1.63nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 1.64nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 1.74nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 1.94nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 2.42nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 2.43nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 2.43nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 3.99nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 4.24nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 5.33nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 5.33nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 5.52nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of CSN5 (unknown origin) using fluorescence-labeled CRL substrate by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 7.40nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 9.06nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Affinity DataIC50: 19.4nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 19.9nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 22.8nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 22.8nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 22.9nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 22.9nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 25.3nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 25.3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 25.3nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 27.4nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 29.9nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Affinity DataIC50: 29.9nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
