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Found 321 with Last Name = 'bulfer' and Initial = 'sl'
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50558084(CHEMBL4799933)
Affinity DataKi:  740nMAssay Description:Uncompetitive inhibition of recombinant human full length Avi-tagged p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2(DE3) using 20 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50558084(CHEMBL4799933)
Affinity DataKi:  3.50E+3nMAssay Description:Competitive inhibition of recombinant human full length Avi-tagged p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2(DE3) using 20 uM A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589660(CHEMBL5193071)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589670(CHEMBL5183210)
Affinity DataIC50:  2nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589694(CHEMBL5170451)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589686(CHEMBL5197168)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589672(CHEMBL5176985)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589678(CHEMBL5181597)
Affinity DataIC50:  3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589669(DCC-3014 | DP-6865 | Dcc-3014 | US11679110, Compou...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of 4 mM ATP measured by cell-based spectrophotometric assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589675(CHEMBL5176270)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589679(CHEMBL5170039)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589661(CHEMBL5200885)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589669(DCC-3014 | DP-6865 | Dcc-3014 | US11679110, Compou...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589674(CHEMBL5186979)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589677(CHEMBL5174778)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589676(CHEMBL5177368)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589680(CHEMBL5195204)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589662(CHEMBL5192630)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589676(CHEMBL5177368)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589675(CHEMBL5176270)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589681(CHEMBL5194023)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589689(CHEMBL5170609)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589692(CHEMBL5175832)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589687(CHEMBL5191635)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589688(CHEMBL5176187)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589660(CHEMBL5193071)
Affinity DataIC50:  8nMAssay Description:Inhibition of CSF1R in CSF1-stimulated human THP-1 cells assessed as inhibition of CSF1R phosphorylation measured by ELISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589693(CHEMBL5177523)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589673(CHEMBL5197530)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589663(CHEMBL5190410)
Affinity DataIC50:  10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589685(CHEMBL5186614)
Affinity DataIC50:  10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50424917(CHEMBL2311578)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human full length Avi-tagged p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2(DE3) using 100 uM ATP as subst...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589672(CHEMBL5176985)
Affinity DataIC50:  12nMAssay Description:Inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589674(CHEMBL5186979)
Affinity DataIC50:  12nMAssay Description:Inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589684(CHEMBL5179072)
Affinity DataIC50:  12nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589659(CHEMBL5197156)
Affinity DataIC50:  12nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589666(CHEMBL5189742)
Affinity DataIC50:  12nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589658(CHEMBL5199944)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589683(CHEMBL5192531)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589653(CHEMBL5171304)
Affinity DataIC50:  14nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589671(CHEMBL5190097)
Affinity DataIC50:  14nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589654(CHEMBL5174705)
Affinity DataIC50:  15nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  17nMAssay Description:Inhibition of CSF1R in CSF1-stimulated human THP-1 cells assessed as inhibition of CSF1R phosphorylation measured by ELISA assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589655(CHEMBL5189828)
Affinity DataIC50:  18nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50468106(CHEMBL4280801 | US11247985, Table 3.49)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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