Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.00200nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate assessed as inhibition...More data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.0480nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate by xanthine oxidase co...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex ...More data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.0780nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:The compound was evaluated for the binding affinity towards dopamine receptor D2 at low affinity state.More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-in...More data for this Ligand-Target Pair
Affinity DataKi: 0.920nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:The compound was evaluated for the binding affinity towards Dopamine receptor D2 at low affinity state.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:The compound was tested for binding activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:The compound was evaluated for the binding affinity towards Dopamine receptor D2 at high affinity state.More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:The compound was evaluated for the dissociation constant for inhibiting the binding of [3H]-SCH- 23390 at Dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University Of Wellington
Curated by ChEMBL
Victoria University Of Wellington
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate by xanthine oxidase co...More data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed on CHO cell membranes after 2 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:The compound was evaluated for the binding affinity towards dopamine receptor D2 at low affinity state.More data for this Ligand-Target Pair