TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Grb2 SH2 domain bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 41nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 46nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 47nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of Grb2 SH2 domain binding by surface plasmon resonanceMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 71nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 122nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of Grb2 SH2 domain bindingMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
Affinity DataIC50: 534nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 621nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 767nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 804nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: 838nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 938nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of [3H]naloxone receptor binding to opioid receptor in the absence of NaClMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Grb2 SH2 domain bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.05E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of radioligand [3H]GR-65630.More data for this Ligand-Target Pair
Affinity DataIC50: 2.09E+3nMAssay Description:Compound was tested for its direct effect on cell-free reverse transcriptase (RT) activity of HIV-1 (LAV-1)More data for this Ligand-Target Pair
Affinity DataIC50: 2.09E+3nMAssay Description:Compound was tested for its direct effect on cell-free reverse transcriptase (RT) activity of HIV-1 (LAV-1)More data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Compound was tested for its direct effect on cell-free reverse transcriptase (RT) activity of HIV-1 (LAV-1)More data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of radioligand [3H]GR-65630.More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of radioligand [3H]GR-65630.More data for this Ligand-Target Pair
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of [3H]naloxone receptor binding to opioid receptor in the absence of NaClMore data for this Ligand-Target Pair
Affinity DataIC50: 2.41E+3nMAssay Description:Melanin concentrating hormone(MCH) activity, causes melanosome aggregation within integumental fish melanocytes and lightening of the skinMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Beijing University Of Technology
Curated by ChEMBL
Beijing University Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: 2.52E+3nMAssay Description:Compound was tested for its direct effect on cell-free reverse transcriptase (RT) activity of HIV-1 (LAV-1)More data for this Ligand-Target Pair
Affinity DataIC50: 2.54E+3nMAssay Description:Effective dose (10 nM) to determine muscarinic nature of the contractile response in guinea pig ileum, when methylatropine was competitively anatgoni...More data for this Ligand-Target Pair
Affinity DataIC50: 2.58E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of radioligand [3H]GR-65630.More data for this Ligand-Target Pair
Affinity DataIC50: 2.72E+3nMAssay Description:Melanin concentrating hormone(MCH) activity, causes melanosome aggregation within integumental fish melanocytes and lightening of the skinMore data for this Ligand-Target Pair