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Found 215 with Last Name = 'corona' and Initial = 'p'
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50143314((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...)
Affinity DataKi:  0nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.000340nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515333(CHEMBL4460815)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515321(CHEMBL4543232)
Affinity DataKi:  0.0310nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515320(CHEMBL4441630)
Affinity DataKi:  0.0420nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515326(CHEMBL4565381)
Affinity DataKi:  0.0440nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515327(CHEMBL4556523)
Affinity DataKi:  0.0510nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515322(CHEMBL4444866)
Affinity DataKi:  0.106nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50143314((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515334(CHEMBL4581470)
Affinity DataKi:  0.196nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM21392(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK cell membrane incubated for 120 mins by microplate beta scintillation coun...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515325(CHEMBL4453342)
Affinity DataKi:  0.315nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515328(CHEMBL4435435)
Affinity DataKi:  0.366nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515324(CHEMBL4447564)
Affinity DataKi:  0.404nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515335(CHEMBL4532589)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515332(CHEMBL4462607)
Affinity DataKi:  0.828nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Antagonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50406804(CHEMBL4177192)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain cerebral cortex membrane incubated for 75 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515331(CHEMBL4530364)
Affinity DataKi:  0.985nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515329(CHEMBL4571320)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM78940(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515330(CHEMBL4476500)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM29525(3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...)
Affinity DataKi:  1.40nMAssay Description:Antagonist activity at 5-HT4 receptor in human HeLa cells assessed as inhibition of intracellular calcium mobilization incubated for 2 hrs by FLIPR a...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM78940(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]SB269970 from human 5-HT7 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515323(CHEMBL4472986)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50402704(CHEMBL2207369)
Affinity DataKi:  7.80nMAssay Description:Antagonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50614136(CHEMBL5287809)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515321(CHEMBL4543232)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515326(CHEMBL4565381)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398391(CHEMBL2178602)
Affinity DataKi:  30nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398394(CHEMBL1232702)
Affinity DataKi:  37nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515327(CHEMBL4556523)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515320(CHEMBL4441630)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398392(CHEMBL2178603)
Affinity DataKi:  60nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515334(CHEMBL4581470)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50614134(CHEMBL5275931)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50614142(CHEMBL5285645)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398390(CHEMBL2177120)
Affinity DataKi:  78nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50614137(CHEMBL5281673)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515333(CHEMBL4460815)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50614144(CHEMBL5282158)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50251158(2-[(3,4,5-Trimethoxy-phenyl)amino]-3-phenyl-5,7-di...)
Affinity DataKi:  100nMAssay Description:Inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398389(CHEMBL2178601)
Affinity DataKi:  100nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398395(CHEMBL1232399)
Affinity DataKi:  100nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515325(CHEMBL4453342)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))TBA
LigandPNGBDBM50614143(CHEMBL5283896)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515328(CHEMBL4435435)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515322(CHEMBL4444866)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50515324(CHEMBL4447564)
Affinity DataKi:  123nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50614138(CHEMBL5283494)
Affinity DataKi:  123nMAssay Description:Competitive inhibition of human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by varing concentratio...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
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