Affinity DataKi: 6nMAssay Description:Binding affinity to human mu opioid receptor by radio-ligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Displacement of [125I]cyanopindolol from human cloned beta-1 adrenergic receptor expressed in Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.59E+3nMAssay Description:Displacement of [125I]cyanopindolol from human cloned beta-2 adrenergic receptor expressed in Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Receptor binding assay(Beta-2 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Receptor binding assay(Beta-1 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Receptor binding assay(Beta-1 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Trevena
Curated by ChEMBL
Trevena
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human Nav 1.5 phasic ion channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Receptor binding assay(Beta-1 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...More data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Receptor binding assay(Beta-2 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Trevena
Curated by ChEMBL
Trevena
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human Nav 1.5 phasic ion channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(RAT)
Burroughs Wellcome
Curated by ChEMBL
Burroughs Wellcome
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+4nMAssay Description:Receptor binding assay(Beta-2 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...More data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of human Nav 1.5 tonic ion channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Nav 1.5 tonic ion channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Trevena
Curated by ChEMBL
Trevena
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human Cav 1.2 ion channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Trevena
Curated by ChEMBL
Trevena
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Cav 1.2 ion channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 631nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 79nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.98E+3nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 5.01E+3nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.59E+3nMAssay Description:Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.25nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.26E+3nMAssay Description:Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.98E+3nMAssay Description:Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 2.51E+3nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+4nMAssay Description:Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 794nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: <794nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair