TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Mixed type inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 7.00E+3nMAssay Description:Mixed type inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Mixed type inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 2.60E+4nMAssay Description:Mixed type inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 2.80E+4nMAssay Description:Mixed type inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 3.10E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 3.70E+4nMAssay Description:Mixed type inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 5.10E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 5.60E+4nMAssay Description:Mixed type inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 8.00E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 1.45E+5nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataKi: 1.47E+5nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
UniversitÉ
Curated by ChEMBL
UniversitÉ
Curated by ChEMBL
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite gr...More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at GFP tagged-human P2Y1 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Agonist activity at GFP tagged-human P2Y11 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 3.30E+3nMAssay Description:Agonist activity at GFP tagged-human P2Y11 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluoresce...More data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitati...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitati...More data for this Ligand-Target Pair
Affinity DataEC50: 1.72E+4nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitati...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitation ...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitati...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at rat pancreas P2Y1 receptor assessed as enhancement of insulin secretionMore data for this Ligand-Target Pair
Affinity DataEC50: 640nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitatio...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:Agonist activity at GFP tagged-human P2Y1 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 9.00E+3nMAssay Description:Agonist activity at GFP tagged-human P2Y1 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Agonist activity at GFP tagged-human P2Y1 receptor expressed in human 1321N1 cells assessed as elevation in calcium level after 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 132N1 receptor assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 980nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 132N1 receptor assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 570nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 132N1 receptor assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.13E+3nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 132N1 receptor assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 9.54E+3nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 132N1 receptor assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 760nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 132N1 receptor assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 132N1 receptor assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at P2Y1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 460nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 480nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitatio...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Agonist activity at P2Y1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 570nMAssay Description:Agonist activity at turkey P2Y1 receptor expressed in human 132N1 receptor assessed as induction of intracellular calcium mobilizationMore data for this Ligand-Target Pair