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Found 83 with Last Name = 'ergüden' and Initial = 'j'
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171626(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  39nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118338(US8653111, 62)
Affinity DataIC50:  50nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171614(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  66nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171633(1-(2-Fluoro-benzyl)-5-[2-(1-methyl-cyclopentyl)-ac...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171611(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171630(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171629(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171615(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171613(5-(3,3-Dimethyl-butyrylamino)-1-(2-trifluoromethyl...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3527(US8524699, 18)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171824(US9085572, 34)
Affinity DataIC50:  180nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118341(US8653111, 85)
Affinity DataIC50:  190nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171643(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171628(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  210nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171637(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171624(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109268(US8609698, 10)
Affinity DataIC50:  260nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171612(5-(2-Bicyclo[2.2.1]hept-2-yl-acetylamino)-1-(2-flu...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118328(US8653111, 7)
Affinity DataIC50:  340nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118344(US8653111, 103)
Affinity DataIC50:  350nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118346(US8653111, 129)
Affinity DataIC50:  360nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171631(4-{[5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benz...)
Affinity DataIC50:  390nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171821(US9085572, 6)
Affinity DataIC50:  430nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171642(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  440nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3543(US8524699, 16)
Affinity DataIC50:  480nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118339(US8653111, 72)
Affinity DataIC50:  490nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118329(US8653111, 10)
Affinity DataIC50:  500nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118331(US8653111, 17)
Affinity DataIC50:  560nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171632(1-(2,6-Difluoro-benzyl)-5-(3,3-dimethyl-butyrylami...)
Affinity DataIC50:  650nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171616(5-(3,3-Dimethyl-thiobutyrylamino)-1-(2-fluoro-benz...)
Affinity DataIC50:  660nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118347(US8653111, 166)
Affinity DataIC50:  690nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3555(US8524699, 3)
Affinity DataIC50:  700nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171827(US9085572, 46)
Affinity DataIC50:  700nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171640(5-(4,4-Dimethyl-pentanoylamino)-1-(2-fluoro-benzyl...)
Affinity DataIC50:  740nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118345(US8653111, 113)
Affinity DataIC50:  740nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118330(US8653111, 12)
Affinity DataIC50:  750nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171823(US9085572, 26)
Affinity DataIC50:  760nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118333(US8653111, 45)
Affinity DataIC50:  780nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171638(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  850nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171621(1-Cyclohexylmethyl-5-(3,3-dimethyl-butyrylamino)-1...)
Affinity DataIC50:  860nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM171822(US9085572, 23)
Affinity DataIC50:  860nMpH: 7.5Assay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3591(US8524699, 7)
Affinity DataIC50:  880nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3623(US8524699, 28)
Affinity DataIC50:  890nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109271(US8609698, 65)
Affinity DataIC50:  900nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM109269(US8609698, 18)
Affinity DataIC50:  910nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3629(US8524699, 46)
Affinity DataIC50:  930nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118337(US8653111, 61)
Affinity DataIC50:  1.10E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM3643(US8524699, 44)
Affinity DataIC50:  1.12E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171641(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM118336(US8653111, 60)
Affinity DataIC50:  1.40E+3nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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