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Found 246 with Last Name = 'fang' and Initial = 'b'
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50044977(CHEMBL3334621)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615452(CHEMBL5271151)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Flt4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551665(CHEMBL4740664)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551664(CHEMBL4761612)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615449(CHEMBL5291434)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564969(CHEMBL4799113)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551667(CHEMBL4752320)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615454(CHEMBL5269747)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of Ron (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564965(CHEMBL4790582)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of Ron (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564967(CHEMBL4778488)
Affinity DataIC50:  4nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615451(CHEMBL5270334)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564969(CHEMBL4799113)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of VEGFR 2 (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604028(CHEMBL5173185 | US20230312529, Compound 6f)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551666(CHEMBL4799621)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  5nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  5nMAssay Description:Inhibition of FLT-4 (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564963(CHEMBL4790980)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of FLT-3 (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604028(CHEMBL5173185 | US20230312529, Compound 6f)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564936(CHEMBL4790688)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of PDGFR alpha (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564968(CHEMBL4783511)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604029(CHEMBL5176371 | US20230312529, Compound 6a)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564964(CHEMBL4789479)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564969(CHEMBL4799113)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of FLT-3 (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551668(CHEMBL4763363)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604031(CHEMBL5208704 | US20230312529, Compound 6g)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551669(CHEMBL4795132)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551670(CHEMBL4795991)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564966(CHEMBL4783902)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564962(CHEMBL4795003)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50551658(CHEMBL4777622)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Harbin Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50564934(CHEMBL4795288)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr)4:1 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615455(CHEMBL5286080)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615447(CHEMBL5289059)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
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