TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibition of matripase (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0910nMAssay Description:Displacement of 2-[125I]iodomelatonin from human recombinant MT1 expressed in CHO cell membranes incubated for 60 mins by liquid scintillation spectr...More data for this Ligand-Target Pair
Affinity DataKi: 0.0910nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-1 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Displacement of [125l]-lodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of 2-[125I]iodomelatonin from human recombinant MT2 expressed in CHO cell membranes incubated for 60 mins by liquid scintillation spectr...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.203nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Displacement of [125l]-lodomelatonin from human MT1 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.302nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]PK11195 from TSPO in rat C6 cell membrane after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of hepsin (unknown origin) using Boc-QAR-AMC as substrate after 30 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.884nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 0.980nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Competitive inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [125I] alpha bungarotoxin from human neuronal alpha4beta2 nAChR expressed in human SH-SY5Y cell membrane measured after 120 mins by T...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PK11195 from TSPO in rat C6 cell membrane after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.69nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-1 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair
Affinity DataKi: 2.68nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.01nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of 2-[125I]iodomelatonin from human recombinant MT2 expressed in CHO cell membranes incubated for 60 mins by liquid scintillation spectr...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [125l]-lodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4.06nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair
Affinity DataKi: 4.27nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Inhibition of matripase (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.64nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 4.77nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 4.77nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 4.90nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-1 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [125l]-lodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.78nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.84nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 8.82nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair