Compile Data Set for Download or QSAR
maximum 50k data
Found 40 with Last Name = 'frasch' and Initial = 'ac'
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467188(CHEMBL4295254)
Affinity DataKi:  1.40E+5nMAssay Description:Non-competitive inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using varying levels...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467190(CHEMBL4284599)
Affinity DataKi:  1.90E+5nMAssay Description:Non-competitive inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using varying levels...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467187(CHEMBL4279251)
Affinity DataKi:  4.30E+5nMAssay Description:Non-competitive inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using varying levels...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50118216((4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl di...)
Affinity DataKi:  7.30E+6nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50118216((4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl di...)
Affinity DataKi:  7.30E+6nMAssay Description:Inhibition of Trypanosoma cruzi trans-sialidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Affinity DataKi:  1.23E+7nMAssay Description:Inhibition of recombinant Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate after 10 mins in prese...More data for this Ligand-Target Pair
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Affinity DataKi:  1.23E+7nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50174837(4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone |...)
Affinity DataIC50:  900nMAssay Description:Inhibition of Trypanosoma cruzi trans-sialidase using CF3MuSA as substrate by UV/visible spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266507(3-(benzo[d]thiazol-2-yl)-4-(2,5-dimethylphenyl)but...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266479(3-(benzo[d]thiazol-2-yl)-4-(3-fluorophenyl)but-3-e...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266386(3-(benzo[d]thiazol-2-yl)-4-(2-isopropoxyphenyl)but...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266509(3-(benzo[d]thiazol-2-yl)-4-(3-(trifluoromethyl)phe...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266506(3-(benzo[d]thiazol-2-yl)-4-(2-ethoxyphenyl)but-3-e...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266478(3-(benzo[d]thiazol-2-yl)-4-(3,4-dimethoxyphenyl)bu...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467188(CHEMBL4295254)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266444(2-(4,5-dimethyl-3-(propoxycarbonyl)thiophen-2-ylca...)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467190(CHEMBL4284599)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467196(CHEMBL4283535)
Affinity DataIC50:  2.70E+5nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266334(2-(2-acetyl-5-tert-butylthiophen-3-ylcarbamoyl)ben...)
Affinity DataIC50:  2.70E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266335((5-(2-(benzo[d][1,3]dioxol-5-ylamino)-2-oxoethylth...)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266510(2-(2-acetylthiophen-3-ylcarbamoyl)benzoate | cid_2...)
Affinity DataIC50:  2.90E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266386(3-(benzo[d]thiazol-2-yl)-4-(2-isopropoxyphenyl)but...)
Affinity DataIC50:  2.90E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by TIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467192(CHEMBL4280072)
Affinity DataIC50:  2.90E+5nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266477(3-(benzo[d]thiazol-2-yl)-4-(3-methoxyphenyl)but-3-...)
Affinity DataIC50:  3.10E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by MuNANA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266506(3-(benzo[d]thiazol-2-yl)-4-(2-ethoxyphenyl)but-3-e...)
Affinity DataIC50:  4.20E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by TIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM4733(5-Acetylamino-6-aminopyridine-2-carboxylic acid | ...)
Affinity DataIC50:  4.40E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467187(CHEMBL4279251)
Affinity DataIC50:  4.70E+5nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467194(CHEMBL4294788)
Affinity DataIC50:  5.10E+5nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266508(3-(benzo[d]thiazol-2-yl)-4-(3-hydroxyphenyl)but-3-...)
Affinity DataIC50:  5.20E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-Sialidase by TIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266705(4-acetamido-3-(hydroxymethyl)benzoate)
Affinity DataIC50:  5.40E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50377984(Cephulac Syrup | Cholac | Chronulac | Constilac | ...)
Affinity DataIC50:  5.70E+5nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467195(CHEMBL4286891)
Affinity DataIC50:  6.30E+5nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467191(CHEMBL4287976)
Affinity DataIC50:  7.10E+5nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSialidase A(Streptococcus pneumoniae)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467188(CHEMBL4295254)
Affinity DataIC50:  1.41E+6nMAssay Description:Inhibition of Streptococcus pneumoniae neuraminidase A using MuNANA as substrate pretreated for 10 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266707((3S,4S,5R)-4-acetamido-3,5-dihydroxycyclohex-1-eny...)
Affinity DataIC50:  1.50E+6nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467197(CHEMBL4289914)
Affinity DataIC50:  2.35E+6nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSialidase(Clostridium perfringens)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467188(CHEMBL4295254)
Affinity DataIC50:  2.39E+6nMAssay Description:Inhibition of Clostridium perfringens neuraminidase using MuNANA as substrate pretreated for 10 mins followed by substrate addition by fluorescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50266703(ethyl (3S,4R,5R)-4-acetamido-3-hydroxy-5-(2-hydrox...)
Affinity DataIC50:  5.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi trans-SialidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467189(CHEMBL4291378)
Affinity DataIC50:  5.58E+6nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrans-sialidase(Trypanosoma cruzi)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50467193(CHEMBL4289944)
Affinity DataIC50: >7.50E+6nMAssay Description:Inhibition of recombinant HisA-tagged Trypanosoma cruzi trans-sialidase expressed in Escherichia coli BL21 (DE3) using MuNANA as substrate pretreated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed