Affinity DataKi: 0.620nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 3 receptor was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 3 receptor was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity towards 5-HT4 receptor in striatum membranes of guinea-pig brain was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 11.2nMAssay Description:Binding affinity towards 5-HT3 receptor in rat was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 13.8nMAssay Description:Binding affinity towards 5-HT3 receptor in rat was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity towards 5-HT3 receptor in rat was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of AChE (unknown orign) by Lineweaver-Burke plotMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor in striatum membranes of guinea-pig brain was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor in striatum membranes of guinea-pig brain was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity towards Dopamine receptor D2 in rat was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Binding affinity towards 5-HT4 receptor in striatum membranes of guinea-pig brain was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 327nMAssay Description:Binding affinity towards D2 receptor in rat was evaluatedMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 621nMAssay Description:Mixed-type inhibition of Electrophorus electricus AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 842nMAssay Description:Binding affinity towards D2 receptor in rat was evaluatedMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataKi: 7.10E+3nMAssay Description:Competitive inhibition of equine serum BChE using acetylthiocholine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 0.0250nMAssay Description:Inhibition of mitochondrial MAO-B in rat liver homogenates using [14C]-phenylethylamine as substrate preincubated for 30 mins by liquid scintillation...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 0.790nMAssay Description:Inhibition of mitochondrial MAO-A in rat liver homogenates using [14C]-(5-hydroxy-triptamine) as substrate preincubated for 30 mins by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodide as substrate preincubated for 10 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Inhibition of AChE in human erythrocytes by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 13.4nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of mitochondrial MAO-B in rat liver homogenates using [14C]-phenylethylamine as substrate preincubated for 30 mins by liquid scintillation...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of propidium iodide from AChE in bovine erythrocytes after 15 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition by Ellman'...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of mitochondrial MAO-B in rat liver homogenates using [14C]-phenylethylamine as substrate preincubated for 30 mins by liquid scintillation...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of mitochondrial MAO-B in rat liver homogenates using [14C]-phenylethylamine as substrate preincubated for 30 mins by liquid scintillation...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of mitochondrial MAO-A in rat liver homogenates using [14C]-(5-hydroxy-triptamine) as substrate preincubated for 30 mins by liquid scintil...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Displacement of propidium iodide from AChE in bovine erythrocytes after 15 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of mitochondrial MAO-B in rat liver homogenates using [14C]-phenylethylamine as substrate preincubated for 30 mins by liquid scintillation...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of mitochondrial MAO-B in rat liver homogenates using [14C]-phenylethylamine as substrate preincubated for 30 mins by liquid scintillation...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodide as substrate preincubated for 10 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Displacement of propidium iodide from AChE in bovine erythrocytes after 15 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of AChE in human erythrocytes by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of mitochondrial MAO-A in rat liver homogenates using [14C]-(5-hydroxy-triptamine) as substrate preincubated for 30 mins by liquid scintil...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: >100nMAssay Description:Inhibition of mitochondrial MAO-B in rat liver homogenates using [14C]-phenylethylamine as substrate preincubated for 30 mins by liquid scintillation...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Displacement of propidium iodide from AChE in bovine erythrocytes after 15 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of mitochondrial MAO-A in rat liver homogenates using [14C]-(5-hydroxy-triptamine) as substrate preincubated for 30 mins by liquid scintil...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of mitochondrial MAO-A in rat liver homogenates using [14C]-(5-hydroxy-triptamine) as substrate preincubated for 30 mins by liquid scintil...More data for this Ligand-Target Pair