Affinity DataKi: 21nMAssay Description:Inhibition of bovine AChE at 30 nM using S-acetylthiocholine as as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Affymax Research Institute
Curated by ChEMBL
Affymax Research Institute
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Compound was tested for inhibition of yeast phosphomannose isomerase (PMI)More data for this Ligand-Target Pair
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Affymax Research Institute
Curated by ChEMBL
Affymax Research Institute
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Compound was tested for inhibition of human phosphomannose isomerase (PMI)More data for this Ligand-Target Pair
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Affymax Research Institute
Curated by ChEMBL
Affymax Research Institute
Curated by ChEMBL
Affinity DataKi: 2.60E+4nMAssay Description:Compound was evaluated for the inhibition constant against phosphomannose isomerase enzyme of Candida albicans (CaPMI)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of arachidonic acid induced TXB2 generation in isolated human platelets (Prostaglandin G/H synthase 1 cell assay)More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PGE-2 generation in LPS-stimulated human monocytes (Prostaglandin G/H synthase 2 cell assay)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of PGE-2 generation in LPS-stimulated human monocytes (Prostaglandin G/H synthase 2 cell assay)More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 141nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 149nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 163nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 163nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 183nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 202nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 206nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of PGE-2 generation in LPS-stimulated human monocytes (Prostaglandin G/H synthase 2 cell assay)More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibitory effect on Prostaglandin G/H synthase 1 activity was evaluated in human whole blood as TXB2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 247nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair