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Found 169 with Last Name = 'gibson' and Initial = 'w'
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049168((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity of the compound against L1210 Thymidylate synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408128(CHEMBL30179)
Affinity DataKi:  0.210nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408130(CHEMBL35926)
Affinity DataKi:  0.350nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049159((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataKi:  0.920nMAssay Description:Binding affinity of the compound against L1210 Thymidylate synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408122(CHEMBL37106)
Affinity DataKi:  1.10nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408135(CHEMBL288666)
Affinity DataKi:  2nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408136(CHEMBL291084)
Affinity DataKi:  2.60nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408129(CHEMBL289749)
Affinity DataKi:  3nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408127(CHEMBL264609)
Affinity DataKi:  4nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408123(CHEMBL36433)
Affinity DataKi:  8.20nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408126(CHEMBL36721)
Affinity DataKi:  8.60nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408125(CHEMBL288615)
Affinity DataKi:  11nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408133(CHEMBL287693)
Affinity DataKi:  18nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408131(CHEMBL36426)
Affinity DataKi:  23nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408132(CHEMBL284613)
Affinity DataKi:  35nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408124(CHEMBL34857)
Affinity DataKi:  42nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408134(CHEMBL35941)
Affinity DataKi:  50nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049159((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049168((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183224(3-[6-(2-dimethylamino-1-imidazol-1-yl-butyl)-napht...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183243(1-((6-((1R,2R)-2-(diethylamino)-1-(1H-imidazol-1-y...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183229(1-((6-((1R,2R)-1-(1H-imidazol-1-yl)-2-(isopropyl(m...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049170((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049172((R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[(2-methyl-4-ox...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049164((S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049176((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049175((S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183237(3-(6-((1R,2R)-1-(1H-imidazol-1-yl)-2-(isopropyl(me...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183231(1-((6-((1R,2R)-2-(ethyl(methyl)amino)-1-(1H-imidaz...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049167((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049165((R)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183225(3-(6-((1R,2R)-2-(diethylamino)-1-(1H-imidazol-1-yl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183228(1-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049158((R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[methyl-(2-meth...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183241(3-(6-((1R,2R)-2-(ethyl(methyl)amino)-1-(1H-imidazo...)
Affinity DataIC50:  9nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049162((R)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049162((R)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183230(1-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049161((S)-4-((R)-1-Carboxy-ethylcarbamoyl)-2-{4-[(2-meth...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049160((S)-4-((S)-1-Carboxy-ethylcarbamoyl)-2-{4-[(2-meth...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049166((R)-2-((S)-4-Carboxy-4-{4-[ethyl-(2-methyl-4-oxo-3...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375331(CHEMBL261253)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375334(CHEMBL411074)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049173((S)-4-((S)-1-Carboxy-2-phenyl-ethylcarbamoyl)-2-{4...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375339(CHEMBL258648)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375337(CHEMBL413828)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(CHEMBL410659 | cis-3-(3-(azetidin-1-ylmethyl)cyclo...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183226(3-[6-(2-dimethylamino-1-imidazol-1-yl-propyl)-naph...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375336(CHEMBL411062)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183232((R)-3-(6-(2-(dimethylamino)-1-(1H-imidazol-1-yl)-2...)
Affinity DataIC50:  26nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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