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Found 123 with Last Name = 'giuntini' and Initial = 's'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)
Affinity DataKi:  43nMAssay Description:Binding affinity to 6xHis-taged MDM2 (unknown origin) expressed in Escherichia coli Gold (DE3) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287688(CHEMBL4173382)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287724(CHEMBL4163249)
Affinity DataIC50:  0.790nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287726(CHEMBL4177354)
Affinity DataIC50:  0.910nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287989(CHEMBL4173588)
Affinity DataIC50:  0.910nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287687(CHEMBL4163281)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287917(CHEMBL4166720)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287706(CHEMBL4173995)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287705(CHEMBL4169540)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287990(CHEMBL4165669)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287988(CHEMBL4167167)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287896(CHEMBL4170132)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287986(CHEMBL4164619)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241617(CHEMBL4068667)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287987(CHEMBL4167230)
Affinity DataIC50:  4nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287725(CHEMBL4162220)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241630(CHEMBL4065471)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241631(CHEMBL4095983)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50241631(CHEMBL4095983)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50582862(CHEMBL5081456)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of PD-1/PDL-1 (unknown origin) bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50241618(CHEMBL4064911)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50241623(CHEMBL4102803)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241627(CHEMBL4105199)
Affinity DataIC50:  10nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241621(CHEMBL4095042)
Affinity DataIC50:  11nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50582861(CHEMBL5093056)
Affinity DataIC50:  12nMAssay Description:Inhibition of PD-1/PDL-1 (unknown origin) bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287990(CHEMBL4165669)
Affinity DataIC50:  12nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287688(CHEMBL4173382)
Affinity DataIC50:  13nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50241629(CHEMBL4100348)
Affinity DataIC50:  14nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50582860(CHEMBL5078455)
Affinity DataIC50:  15nMAssay Description:Inhibition of PD-1/PDL-1 (unknown origin) bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287917(CHEMBL4166720)
Affinity DataIC50:  18nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50239947(CHEMBL4089730 | US20230303494, Compound BMS202 | U...)
Affinity DataIC50:  18nMAssay Description:Inhibition of PD-1/PDL-1 (unknown origin) bindingMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50241626(CHEMBL4080951)
Affinity DataIC50:  19nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287989(CHEMBL4173588)
Affinity DataIC50:  20nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287725(CHEMBL4162220)
Affinity DataIC50:  22nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50239947(CHEMBL4089730 | US20230303494, Compound BMS202 | U...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant PD-1/PDL-1 interaction measured by HTRF assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287705(CHEMBL4169540)
Affinity DataIC50:  22nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287726(CHEMBL4177354)
Affinity DataIC50:  22nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50241628(CHEMBL4084848)
Affinity DataIC50:  23nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241626(CHEMBL4080951)
Affinity DataIC50:  23nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287986(CHEMBL4164619)
Affinity DataIC50:  28nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287724(CHEMBL4163249)
Affinity DataIC50:  31nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50241627(CHEMBL4105199)
Affinity DataIC50:  35nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287987(CHEMBL4167230)
Affinity DataIC50:  36nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287687(CHEMBL4163281)
Affinity DataIC50:  40nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287988(CHEMBL4167167)
Affinity DataIC50:  41nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50241622(CHEMBL4074577)
Affinity DataIC50:  43nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287990(CHEMBL4165669)
Affinity DataIC50:  45nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287706(CHEMBL4173995)
Affinity DataIC50:  48nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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