Affinity DataKi: 0.000350nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.000400nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.00900nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0140nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Binding affinity to N-terminal 6-His tagged human LRH-1 LBD (299 to 541 residues) expressed in Escherichia coli BL21-(DE3) assessed as inhibition con...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]estradiol from ERalpha after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Binding affinity to ERalpha ligand binding domainMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]estradiol from ERalpha after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Binding affinity to ERalpha ligand binding domainMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Displacement of [3H]estradiol from ERalpha after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]estradiol from ERbeta after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry
Curated by ChEMBL
School Of Natural Sciences--Chemistry
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 1nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 1nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 1nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity to N-terminal 6-His tagged human LRH-1 LBD (299 to 541 residues) expressed in Escherichia coli BL21-(DE3) assessed as inhibition con...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
Affinity DataKi: 2nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 2nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 2nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 2nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 2nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 2nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 2nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
Affinity DataKi: 2.74nMAssay Description:Displacement of [3H]estradiol from ERbeta after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human Poly (ADP-ribose) polymerase 1 enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Binding affinity to N-terminal 6-His tagged human LRH-1 LBD (299 to 541 residues) expressed in Escherichia coli BL21-(DE3) assessed as inhibition con...More data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1)More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair