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Found 73 with Last Name = 'harrak' and Initial = 'y'
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  100nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326520(1-(4-(methylsulfonyl)phenyl)-1H-indole | CHEMBL124...)
Affinity DataIC50:  300nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  780nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326527((4-bromophenyl)(4-(methylsulfonyl)phenyl)methanone...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326525(2-(4-(methylsulfonyl)phenyl)pyridine | CHEMBL12409...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213558(2-[N-(2,3-dihydro-1,4-benzodioxin-6-yl)-pyrrol-2-y...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of COX1 in human whole blood after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326523(4-fluoro-N-(4-(methylsulfonyl)phenyl)aniline | CHE...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213558(2-[N-(2,3-dihydro-1,4-benzodioxin-6-yl)-pyrrol-2-y...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of COX2 in human whole blood after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213559(2-(N-(2-Ffuorophenyl)pyrrol-3-yl) acetic acid | CH...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of COX2 in human whole blood after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326534(CHEMBL1240537 | furan-3-yl(4-(methylsulfonyl)pheny...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDehydrogenase/reductase SDR family member 9(Rattus norvegicus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213558(2-[N-(2,3-dihydro-1,4-benzodioxin-6-yl)-pyrrol-2-y...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of rat liver 3-alpha-HSD assessed as 5-beta-dihydrocortisone reductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of COX2 in human whole blood after 15 minsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213563(2-(N-(2-fluorophenyl)pyrrol-2-yl) acetic acid | CH...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of COX2 in human whole blood after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  6.86E+3nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of COX1 in human whole blood after 15 minsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326526((4-fluorophenyl)(4-(methylsulfonyl)phenyl)methanon...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326521(1-(4-(methylsulfonyl)phenyl)-1H-pyrrole | CHEMBL12...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326530((1H-indol-3-yl)(4-(methylsulfonyl)phenyl)methanone...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDehydrogenase/reductase SDR family member 9(Rattus norvegicus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50371165(CHEMBL236237)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of rat liver 3-alpha-HSD assessed as 5-beta-dihydrocortisone reductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213559(2-(N-(2-Ffuorophenyl)pyrrol-3-yl) acetic acid | CH...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of COX1 in human whole blood after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213553((S)-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propano...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of COX1 in human whole blood after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326535(2-(p-Methylsulfonylbenzoyl)furan | CHEMBL1240887)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326528((4-(methylsulfonyl)phenyl)(thiophen-3-yl)methanone...)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213553((S)-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propano...)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of COX2 in human whole blood after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDehydrogenase/reductase SDR family member 9(Rattus norvegicus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213563(2-(N-(2-fluorophenyl)pyrrol-2-yl) acetic acid | CH...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of rat liver 3-alpha-HSD assessed as 5-beta-dihydrocortisone reductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326522(1-(4-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)pip...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326535(2-(p-Methylsulfonylbenzoyl)furan | CHEMBL1240887)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326531((1-(2-fluorophenyl)-1H-pyrrol-3-yl)(4-(methylsulfo...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213563(2-(N-(2-fluorophenyl)pyrrol-2-yl) acetic acid | CH...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of COX1 in human whole blood after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326529(2-(p-Methylsulfonylbenzoyl)thiophene | CHEMBL12408...)
Affinity DataIC50:  2.31E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326524(4-(4-(methylsulfonyl)phenyl)-4H-benzo[b]pyrrolo[1,...)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326530((1H-indol-3-yl)(4-(methylsulfonyl)phenyl)methanone...)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDehydrogenase/reductase SDR family member 9(Rattus norvegicus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213559(2-(N-(2-Ffuorophenyl)pyrrol-3-yl) acetic acid | CH...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat liver 3-alpha-HSD assessed as 5-beta-dihydrocortisone reductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326531((1-(2-fluorophenyl)-1H-pyrrol-3-yl)(4-(methylsulfo...)
Affinity DataIC50:  3.46E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326533((1-methyl-1H-indol-3-yl)(4-(methylsulfonyl)phenyl)...)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326532((1-(2-fluorophenyl)-1H-pyrrol-2-yl)(4-(methylsulfo...)
Affinity DataIC50:  4.33E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDehydrogenase/reductase SDR family member 9(Rattus norvegicus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50371167(CHEMBL236030)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of rat liver 3-alpha-HSD assessed as 5-beta-dihydrocortisone reductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  7.32E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326533((1-methyl-1H-indol-3-yl)(4-(methylsulfonyl)phenyl)...)
Affinity DataIC50:  7.64E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326520(1-(4-(methylsulfonyl)phenyl)-1H-indole | CHEMBL124...)
Affinity DataIC50:  7.87E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326522(1-(4-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)pip...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326521(1-(4-(methylsulfonyl)phenyl)-1H-pyrrole | CHEMBL12...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50326525(2-(4-(methylsulfonyl)phenyl)pyridine | CHEMBL12409...)
Affinity DataIC50:  8.96E+4nMAssay Description:Inhibition of sheep COX1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDehydrogenase/reductase SDR family member 9(Rattus norvegicus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50371173(CHEMBL397792)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of rat liver 3-alpha-HSD assessed as 5-beta-dihydrocortisone reductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50213566(2-(2,3-dihydro-1,4-benzodioxin-6-yl) acetic acid |...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1 in human whole blood after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDehydrogenase/reductase SDR family member 9(Rattus norvegicus)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of rat liver 3-alpha-HSD assessed as 5-beta-dihydrocortisone reductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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