TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.770nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant cathepsin K by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% of the Acyl coenzyme A:cholesterol acyltransferase 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin K by fluorometric assayMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant cathepsin K by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of low pH activation of human TRPV1More data for this Ligand-Target Pair
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit liver Acyl coenzyme A:choleste...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of rat CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of low pH activation of rat TRPV1More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit artery Acyl coenzyme A:cholest...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rat liverMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair