Compile Data Set for Download or QSAR
maximum 50k data
Found 537 with Last Name = 'hawkins' and Initial = 'm'
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208224(2-(3-((1-(2-naphthoyl)piperidin-4-yl)(methyl)carba...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208222((E)-2-(3-chloro-5-fluorostyrylamino)-1-(5-chlorobe...)
Affinity DataKi:  11nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208228(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataKi:  36nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208224(2-(3-((1-(2-naphthoyl)piperidin-4-yl)(methyl)carba...)
Affinity DataKi:  38nMAssay Description:Inhibition of human neutrophil Cat GMore data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50208228(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of human neutrophil Cat GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167611((2R,5R)-1-[4-(2-Chloro-4-fluoro-benzyloxy)-benzene...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435525((2R,3S,4R,5R)-2-(((2-amino-3- bromoquinolin-7-yl)o...)
Affinity DataIC50:  0.5nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435525((2R,3S,4R,5R)-2-(((2-amino-3- bromoquinolin-7-yl)o...)
Affinity DataIC50:  0.5nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435525((2R,3S,4R,5R)-2-(((2-amino-3- bromoquinolin-7-yl)o...)
Affinity DataIC50:  0.5nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM584223((2R,3R,4S,5R)-2-(4-amino-5-fluoro- 7H-pyrrolo[2,3-...)
Affinity DataIC50:  0.700nMAssay Description:HotSpot Assay. Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435509((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  0.75nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435509((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  0.75nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435509((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  0.75nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435657((2R,3S,4R,5R)-2-(((2-amino-3- bromoquinolin-7-yl)o...)
Affinity DataIC50:  0.800nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435657((2R,3S,4R,5R)-2-(((2-amino-3- bromoquinolin-7-yl)o...)
Affinity DataIC50:  0.800nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435657((2R,3S,4R,5R)-2-(((2-amino-3- bromoquinolin-7-yl)o...)
Affinity DataIC50:  0.800nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435523((2R,3S,4R,5R)-5-(4-amino-5-fluoro-7H- pyrrolo[2,3-...)
Affinity DataIC50:  0.850nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435523((2R,3S,4R,5R)-5-(4-amino-5-fluoro-7H- pyrrolo[2,3-...)
Affinity DataIC50:  0.850nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435523((2R,3S,4R,5R)-5-(4-amino-5-fluoro-7H- pyrrolo[2,3-...)
Affinity DataIC50:  0.850nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435710((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  0.900nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435710((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  0.900nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435710((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  0.900nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM452999((2S,3S,4R,5R)-2-((R)-6- chloro-1,3- dihydroisobenz...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM452998((2R,3R,4S,5S)-2-(4-amino- 7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435709((2R,3S,4R,5R)-3-methyl-5-(4-methyl-7H- pyrrolo[2,3...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435709((2R,3S,4R,5R)-3-methyl-5-(4-methyl-7H- pyrrolo[2,3...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM452999((2S,3S,4R,5R)-2-((R)-6- chloro-1,3- dihydroisobenz...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM452998((2R,3R,4S,5S)-2-(4-amino- 7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM452999((2S,3S,4R,5R)-2-((R)-6- chloro-1,3- dihydroisobenz...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM452998((2R,3R,4S,5S)-2-(4-amino- 7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435709((2R,3S,4R,5R)-3-methyl-5-(4-methyl-7H- pyrrolo[2,3...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435524((2R,3S,4R,5R)-2-(((2-aminoquinolin-7- yl)oxy)methy...)
Affinity DataIC50:  1.10nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435524((2R,3S,4R,5R)-2-(((2-aminoquinolin-7- yl)oxy)methy...)
Affinity DataIC50:  1.10nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435524((2R,3S,4R,5R)-2-(((2-aminoquinolin-7- yl)oxy)methy...)
Affinity DataIC50:  1.10nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM453006((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.20nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167619((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(4-methyl-benz...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM453006((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.20nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM453006((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.20nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167618((2R,5R)-1-[4-(4-Bromo-benzyloxy)-benzenesulfonyl]-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM453011((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.45nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM453011((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.45nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM453011((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.45nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM452997((2R,3R,4S,5S)-2-(4-amino- 7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.5nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM452997((2R,3R,4S,5S)-2-(4-amino- 7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.5nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435651((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.5nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435651((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.5nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435651((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.5nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM452997((2R,3R,4S,5S)-2-(4-amino- 7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.5nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM453026((2R,3R,4S,5S)-2-(4-amino- 7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.60nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM435518((2R,3S,4R,5R)-5-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  1.60nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 537 total ) | Next | Last >>
Jump to: